Accorinte, M. L. R.Loguercio, A. D.Reis, A.Bauer, J. R. O.Grande, R. H. M.Murata, S. S.Souza, VHolland, R.2014-05-272014-05-272009-02-01International Endodontic Journal, v. 42, n. 2, p. 122-128, 2009.0143-28851365-2591http://hdl.handle.net/11449/70927Aim: The present randomized, controlled prospective study evaluated the histomorphological response of human dental pulps capped with two grey mineral trioxide aggregate (MTA) compounds. Methodology: Pulp exposures were performed on the occlusal floor of 40 human permanent pre-molars. The pulp was capped either with ProRoot (Dentsply) or MTA-Angelus (Angelus) and restored with zinc oxide eugenol cement. After 30 and 60 days, teeth were extracted and processed for histological examination and the effects on the pulp were scored. The data were subjected to Kruskal-Wallis and Conover tests (α = 0.05). Results: In five out of the 40 teeth bacteria were present in pulp tissue. No significant difference was observed between the two materials (P > 0.05) in terms of overall histological features (hard tissue bridge, inflammatory response, giant cells and particles of capping materials). Overall, 94% and 88% of the specimens capped with MTA-Angelus and ProRoot, respectively, showed either total or partial hard tissue bridge formation (P > 0.05). Conclusions: Both commercial materials ProRoot (Dentsply) and MTA-Angelus (Angelus) produced similar responses in the pulp when used for pulp capping in intact, caries-free teeth. © 2009 International Endodontic Journal.122-128engHard tissue bridgeInflammatory responseMineral trioxide aggregatePulp-capping human teethaluminum derivativecalcium derivativemineral trioxide aggregateoxidesilicatetooth cementzinc oxide eugenoladultclinical trialcomparative studycontrolled clinical trialcontrolled studydentin sensitivitydrug combinationdrug effectendodonticsfollow upgiant cellhumanmicrobiologyodontoblastpathologyprospective studypulpitisrandomized controlled trialsingle blind proceduretooth pulptooth pulp diseaseAdultAluminum CompoundsCalcium CompoundsDental CementsDental PulpDental Pulp CappingDental Pulp ExposureDental Pulp NecrosisDentin SensitivityDentin, SecondaryDrug CombinationsFollow-Up StudiesGiant CellsHumansOdontoblastsOxidesProspective StudiesPulpitisSilicatesSingle-Blind MethodZinc Oxide-Eugenol CementArtigo10.1111/j.1365-2591.2008.01485.xAcesso restrito2-s2.0-58149327293