Pires, Regina Helena [UNESP]Lucarini, RodrigoMendes-Giannini, Maria José Soares [UNESP]2014-05-202014-05-202012-01-01Antimicrobial Agents and Chemotherapy. Washington: Amer Soc Microbiology, v. 56, n. 1, p. 595-597, 2012.0066-4804http://hdl.handle.net/11449/7256The activity of usnic acid against Candida orthopsilosis and Candida parapsilosis on planktonic and biofilm conditions was investigated by using a broth microdilution and microplate methods. Potent in vitro activities against different Candida species were obtained. The metabolic activity of sessile cells of C. parapsilosis complex was reduced by 80% at four times the 80% inhibitory concentration. The in vitro studies support further efforts to determine whether usnic acid can be used clinically to cure patients with Candida infections.595-597engArtigo10.1128/AAC.05348-11WOS:000298404900080Acesso restritoWOS000298404900080.pdf0000-0002-8059-0826