Ribeiro, D. A.Scolastici, C.de Lima, PLAMarques, MEASalvadori, Daisy Maria Favero [UNESP]2014-05-202014-05-202005-05-01Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontics. St Louis: Mosby, Inc., v. 99, n. 5, p. 637-640, 2005.1079-2104http://hdl.handle.net/11449/12825Objective. In the current study, the potential DNA damage associated with exposure to a number of antimicrobial endodontic compounds was assessed by the single cell gel (comet) assay in vitro.Study design. Chinese hamster ovary (CHO) cells were exposed to formocresol, paramonochlorophenol, calcium hydroxide, or chlorhexidine at final concentration ranging from 0.01% to 1%.Results. Formocresol, paramonochlorophenol, and calcium hydroxide, as well as chlorhexidine in all concentrations tested did not contribute to the DNA damage.Conclusion. These findings are clinically relevant since they represent an important contribution to the correct evaluation of the potential health risk associated with exposure to dental agents.637-640engGenotoxicity of antimicrobial endodontic compounds by single cell gel (comet) assay in Chinese hamster ovary (CHO) cellsArtigo10.1016/j.tripleo.2004.07.010WOS:000228655300022Acesso restrito5051118752980903