Montelli, T. C. B.Iwasso, M. T. R.Peracoli, M. T. S.Mota, N. G. S.2014-05-262014-05-261981-01-01Arquivos de Neuro-Psiquiatria, v. 39, n. 1, p. 1-12, 1981.0004-282Xhttp://hdl.handle.net/11449/63509The immunological status of five children with West syndrome consequent to previous cerebral lesions was investigated. Three children had West syndrome and two were in transition from West to Lennox-Gastaut syndrome. All of them showed cellular immunological deficiencies in the following tests: sensitization to DNCB, intracutaneous reaction to PHA, inhibition of leukocyte migration, blastic transformation of lymphocytes, T and B lymphocytes in peripheral blood and levels of serum immunoglobulins. These immunological deficiencies, of different degrees of severity, were associated with frequent infections in these children. A possible association between the immunological deficiencies and autoimmunity is discussed.1-12eng1 chloro 2,4 dinitrobenzeneclonazepamcorticotropinnitrazepamphenobarbitalphytohemagglutininb lymphocytebrain injurycellular immunitycentral nervous systemdrug therapyelectroencephalographyetiologyhumoral immunityimmune deficiencyinfantlennox gastaut syndromemajor clinical studypathogenesispreschool childt lymphocytetherapywest syndromeAntibody FormationCase ReportChild, PreschoolFemaleHumanImmunity, CellularImmunoglobulinsInfantLymphocyte ActivationMaleSkin TestsSpasms, InfantileSyndromeArtigo10.1590/S0004-282X1981000100001S0004-282X1981000100001Acesso aberto2-s2.0-00195003572-s2.0-0019500357.pdf