Barros, Aline Lima deSouza, Vanessa Vilamaior deNavarro, Stephanie DynczukiOesterreich, Silvia AparecidaOliveira, Rodrigo JulianoLeite Kassuya, Candida AparecidaArena, Arielle Cristina [UNESP]2014-12-032014-12-032013-09-02Journal Of Toxicology And Environmental Health-part A-current Issues. Philadelphia: Taylor & Francis Inc, v. 76, n. 17, p. 1003-1006, 2013.1528-7394http://hdl.handle.net/11449/112663This study assessed the genotoxic and mutagenic potential of diflubenzuron (DFB) insecticide in mice. Mice were divided into five groups: group I: negative control; group II: positive control; group III: 0.3 mg/kg of DFB; group IV: 1 mg/kg of DFB; group V: 3 mg/kg DFB. Peripheral blood was collected for the comet assay and the micronucleus (MN) test. DFB increased incidence of comet formation at all doses tested. A rise in the frequency of MN in mouse peripheral blood was observed 24, 48, and 72 h postexposure at all doses tested. Data demonstrate that DFB exerts genotoxic and mutagenic effects in a dose-dependent manner.1003-1006engArtigo10.1080/15287394.2013.830585WOS:000326222200001Acesso restrito0729220781785349