Balbi, A. P CCampos, K. E. [UNESP]Alves, M. J Q F [UNESP]2014-05-272014-05-272008-12-01Revista Brasileira de Plantas Medicinais, v. 10, n. 3, p. 51-56, 2008.1516-0572http://hdl.handle.net/11449/70795The plant species Phalaris canariensis, known as canary grass, is widely used in folk medicine as diuretic, as well as in culinary and animal feed. In this study, the effect of P. canariensis aqueous extract (AE) on water flow (V) and sodium renal excretion (Qe (Na+)) was evaluated in anesthetized Wistar rats. Arterial pressure alterations (AP) were also assessed. Two groups were studied: Control group (CON) - oral administration of 1.0 mL distilled water, and Experimental group (EA) - oral administration of 1.0 mL P. canariensis aqueous extract 40%. Rats were anesthetized and subjected to cannulation of trachea (for better pulmonary ventilation), left carotid artery (for arterial pressure measurement) and urinary bladder (for urine collection). Control animals did not present significant alterations (p>0.05) in all analyzed parameters after water administration. EA group had a significant arterial pressure reduction at 60 minutes (31.4%) and 90 minutes (49.1%) after the extract administration (p<0.05). Renal parameters did not have any significant alteration (p>0.05). In this study, P. canariensis aqueous extract had a hypotensive effect in anesthetized Wistar rats, without renal alterations.51-56porArterial pressureCanary grassPhalaris canariensisWistar ratantihypertensive agentPhalaris canariensis extractplant extractunclassified druganimal experimentantihypertensive activityarterial pressurecannulationcarotid arterycontrolled studymalenonhumanPhalarisratsodium excretionurinary excretionwater flowAnimaliaPhalaris aquaticaRattusRattus norvegicusArtigoAcesso aberto2-s2.0-779544939672-s2.0-77954493967.pdf