Medina, Rebeca P. [UNESP]de Moura, Vagner M.da Silva, Cleuza C.de Oliveira, Cecília M. A.Kato, LuciliaPomini, Armando M.de Carvalho, João E.Ruiz, Ana Lúcia T. G.Bersani-Amado, Ciomar A.Santin, Silvana M. O.2018-12-112018-12-112018-06-03Natural Product Research, v. 32, n. 11, p. 1357-1360, 2018.1478-64271478-6419http://hdl.handle.net/11449/174792The crude extract and fractions from the branches of Ixora brevifolia, a tree found in the Brazilian Cerrado, were tested for anti-inflammatory and in vitro antiproliferative effects. The crude extract and n-hexane fraction exhibited significant inhibition of ear oedema in mice, while n-hexane-precipitated and chloroform fractions strongly inhibited the myeloperoxidase activity in ear tissue. The n-hexane and n-hexane-precipitated fractions showed strong growth inhibition for glioma cell line and the hydromethanolic fraction inhibited the growth of leukaemia cell line.1357-1360enganti-inflammatory activityantiproliferative activityIxora brevifoliaRubiaceaeArtigo10.1080/14786419.2017.1344654Acesso aberto2-s2.0-850211847272-s2.0-85021184727.pdf