Effects of a continuous rate infusion of butorphanol in isoflurane-anesthetized horses on cardiorespiratory parameters, recovery quality, gastrointestinal motility and serum cortisol concentrations

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Data

2014-12-01

Autores

Dias, Bianca Paludeto [UNESP]
Araújo, Marcelo Augusto de
Deschk, Maurício [UNESP]
Trein, Thomas Alexander [UNESP]
Pinheiro, Nirmem Carlos [UNESP]
Perri, Silvia Helena Venturolli [UNESP]
Rodrigues, Celso Antônio [UNESP]
Santos, Paulo Sergio Patto dos [UNESP]

Título da Revista

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Título de Volume

Editor

Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia

Resumo

PURPOSE: To assess the cardiorespiratory parametes, recovery, gastrointestinal motility and serum cortisol concentrations in horses anesthetized with isoflurane with or without a continuous rate infusion (CRI) of butorphanol for orchiectomy. METHODS: Twelve adult, intact, male horses weighing 332 ± 55 kg were included in the study. Xilazine was administered as premedication. Anesthesia was induced with ketamine and midazolam and maintained with isoflurane. Butorphanol (0.025 mg kg-1 bolus) or an equivalent volume of saline (0.9%) was given intravenously followed by a CRI of butorphanol (BG) (13 µg kg-1 hour-1) or saline (CG). Cardiorespiratory variables were recorded before (T0) and every 15 minutes for 75 minutes after the start of infusion. Serum cortisol concentration was measured at T0 and 60 minutes, and 30 minutes and 19 hours after the horse stood up. Recovery from anesthesia was evaluated using a scoring system. Gastrointestinal motility was evaluated before anesthesia and during 24 hours after recovery. RESULTS: There were no significant differences between groups in cardiopulmonary variables, or recovery scores or serum cortisol concentrations. A reduction in gastrointestinal motility was recorded for 60 minutes in BG. CONCLUSIONS: Continuous rate infusion of butorphanol in horses anesthetized with isoflurane did not adversely affect the cardiopulmonary variables monitored, or recovery scores. A small but statistically significant reduction in gastrointestinal motility occurred in the butorphanol group.

Descrição

Palavras-chave

Blood Gas Analysis, Analgesics, Opioid, Anesthesia, Inhalation, Orchiectomy, Horses

Como citar

Acta Cirurgica Brasileira. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, v. 29, n. 12, p. 801-806, 2014.

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