Bone marrow necrosis related to paracoccidioidomycosis: the first eight cases identified at autopsy
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Data
2009-03-01
Autores
Resende, Lucilene Silva Ruiz e [UNESP]
Mendes, Rinaldo Poncio [UNESP]
Bacchi, Maura Moscardi [UNESP]
Marques, Silvio Alencar [UNESP]
Barraviera, Benedito [UNESP]
Souza, Lenice R. [UNESP]
Meira, Domingos A. [UNESP]
NiƩro-Melo, Ligia [UNESP]
TĆtulo da Revista
ISSN da Revista
TĆtulo de Volume
Editor
Wiley-Blackwell Publishing, Inc
Resumo
To report the first eight bone marrow necrosis (BMN) cases related to paracoccidioidomycosis (PCM) from patient autopsies with well-documented bone marrow (BM) histology and cytology.A retrospective evaluation was performed on BM specimens from eight autopsied patients from Botucatu University Hospital with PCM-related BMN. Relevant BMN literature was searched and analysed.All eight patients had acute PCM. Six had histological only (biopsies) and two cytological only (smears) specimens. Five biopsy specimens revealed severe and one mild coagulation patterned necrotic areas. Five had osteonecrosis. The cytological specimens also showed typical BMN patterns. Paracoccidioides brasiliensis yeast forms were visible within necrotic areas in all cases.
DescriĆ§Ć£o
Palavras-chave
bone marrow, bone marrow necrosis, coagulation necrosis, osteonecrosis, paracoccidioidomycosis
Como citar
Histopathology. Malden: Wiley-blackwell Publishing, Inc, v. 54, n. 4, p. 486-489, 2009.