Associação glicemia de jejum e fatores de risco como teste para rastreamento do diabete gestacional
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Data
2005-09-01
Autores
Ayach, Wilson
Calderon, Iracema de Mattos Paranhos [UNESP]
Rudge, Marilza Vieira Cunha [UNESP]
Costa, Roberto Antonio de Araújo [UNESP]
Título da Revista
ISSN da Revista
Título de Volume
Editor
Instituto de Medicina Integral Prof. Fernando Figueira
Resumo
OBJETIVOS: comparar dois testes de rastreamento do diabete gestacional. MÉTODOS: estudo prospectivo no qual foram avaliadas 356 gestantes, sem diagnóstico prévio do diabete melito, submetidas, de modo independente, a dois testes de rastreamento: associação glicemia de jejum e fator de risco (GJ+FR) e teste oral simplificado de tolerância à glicose (TTG50g). A comparação entre os métodos foi realizada pelos índices de sensibilidade (S), especificidade (E) e valores preditivos positivo (VPP) e negativo (VPN), resultados falsos, positivos (FP) e negativos (FN) e pela diferença dos resultados observados e esperados, avaliada pelo teste do Qui-quadrado (p<0,05). RESULTADOS: a associação GJ+FR determinou a confirmação diagnóstica em maior número de gestantes (187; 52,5%) que o TTG50g (49; 13,8%). Esta diferença foi significativa (p<0,05). A associação GJ+FR apresentou sensibilidade de 83,7% e valor preditivo negativo (VPN) de 95,3% em relação ao TTG50g. CONCLUSÕES: os índices elevados de sensibilidade e VPN da associação GJ+FR em relação ao TTG50g, sua simplicidade, praticidade, baixo custo e fácil replicação permitem sua indicação no rastreamento do diabete gestacional.
OBJECTIVES: compare two gestational diabetes tests. METHODS: a prospective study in which 356 pregnant women, with no previous diabetes mellitus diagnoses independently submitted to two tests; fasting glycemia and risk factor association (FG+RF) and the simplified oral test for glucose tolerance (TTG50g). Methods of comparison were performed by sensitivity (S) and (ES) specificity indexes, positive predictive values (PPV) and negative predictive values (NPV), false results, false positive (FP) and false negative (FN) and by the difference of the results determined and expected, evaluated through the Chi-Square Test (p<0.05). RESULTS: FG+RF association determined diagnostic confirmation in a larger number of patients (187; 52.5%) than TTG50g (49; 13.8%). This difference was significant (p<0.05). The FG+RF association indicated a sensitivity of 83.7% and negative predictive value (NPV) of 95.3% as compared to TTG50g. CONCLUSIONS: the high sensitivity rates and NPV from the association of FG+RF as compared to TTG50g and its simplicity, practicality, low cost and easy replication are positive qualities for gestational diabetes testing indication.
OBJECTIVES: compare two gestational diabetes tests. METHODS: a prospective study in which 356 pregnant women, with no previous diabetes mellitus diagnoses independently submitted to two tests; fasting glycemia and risk factor association (FG+RF) and the simplified oral test for glucose tolerance (TTG50g). Methods of comparison were performed by sensitivity (S) and (ES) specificity indexes, positive predictive values (PPV) and negative predictive values (NPV), false results, false positive (FP) and false negative (FN) and by the difference of the results determined and expected, evaluated through the Chi-Square Test (p<0.05). RESULTS: FG+RF association determined diagnostic confirmation in a larger number of patients (187; 52.5%) than TTG50g (49; 13.8%). This difference was significant (p<0.05). The FG+RF association indicated a sensitivity of 83.7% and negative predictive value (NPV) of 95.3% as compared to TTG50g. CONCLUSIONS: the high sensitivity rates and NPV from the association of FG+RF as compared to TTG50g and its simplicity, practicality, low cost and easy replication are positive qualities for gestational diabetes testing indication.
Descrição
Palavras-chave
Diabete gestacional, Glicemia, Fatores de risco, Teste de tolerância à glicose, Diabetes, gestacional, Blood glucose, Risk factors, Glucose tolerance test
Como citar
Revista Brasileira de Saúde Materno Infantil . Instituto de Medicina Integral Prof. Fernando Figueira, v. 5, n. 3, p. 329-335, 2005.