Connective tissue graft as a biological barrier for guided tissue regeneration in intrabony defects: a histological study in dogs

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Data

2014

Autores

Ribeiro, Fernando Salimon
Pontes, Ana EmÍlia Farias
Zuza, Elizangela Partata
Silva, Vanessa Camila da
Lia, Raphael Carlos Comelli
Marcantonio Júnior, Elcio [UNESP]

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Background The use of the autogenous periosteal graft as biological barrier has been proposed for periodontal regeneration. The aim of this study was to evaluate the histometric findings of the subepithelial connective tissue graft as barrier in intrabony defects compared to a bioabsorbable membrane. Methods Three-walled intrabony defects were created surgically in the mesial aspect of the right and left maxillary canines in five healthy mongrel dogs. The defects were chronified, and two types of barriers were randomly carried out for guided tissue regeneration in a split-mouth design: the test group with a subepithelial connective tissue graft and the control group with a bioabsorbable membrane. The specimens were processed for histometric analyses of the epithelium (E), connective tissue (CT), newly formed cementum (NC), new bone (NB), and total newly formed tissues (NFT). Results The test side showed smaller mean of NC (3.6±1.2), NB (2.1±0.7), and NFT (7.7±0.8) than the control group (NC 7.3±0.5; NB 5.3±1.3; NFT 10.1±2.2; P<0.05). No statistically significant differences were verified for E (test 3.1±2.0; control 2.8±2.1; P>0.05) and CT (test 2.5±1.1; control 2.0± 0.5; P>0.05) between groups

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Connective tissue graft(s), Guided tissue regeneration, Periodontal regeneration, Histology

Como citar

Clinical Oral Investigations, v. 19, n. 5, p. 997–1004, 2014.