Unusual C,O-fused glycosylapigenins from serjania marginata leaves
Carregando...
Fontes externas
Fontes externas
Data
Orientador
Coorientador
Pós-graduação
Curso de graduação
Título da Revista
ISSN da Revista
Título de Volume
Editor
Amer Chemical Soc
American Chemical Society (ACS)
American Chemical Society (ACS)
Tipo
Artigo
Direito de acesso
Acesso restrito
Fontes externas
Fontes externas
Resumo
A phytochemical study of a Serjania marginata leaf extract with antiulcer activity afforded 15 compounds, including the new 3-O-alpha-L-arabinopyranosyl(1 -> 3)-alpha-L-rhamnopyranosyl(1 -> 2)[beta-D-glucopyranosyl(1 -> 4)]-alpha-L-arabinopyranosyloleanolic acid (1) and 7,5 "-anhydroapigenin 8-C-alpha-(2,6-dideoxy-5-hydroxy-ribo-hexopyranosyl)-4'-O-beta-D-glucopyranoside (4). The structures of the new compounds were determined by spectroscopic analysis, including 1D and 2D NMR techniques, mass spectrometry, and chemical methods. Compound 4 is a C-hexopyranosylapigenin with an unusual cyclic ether linkage between C-5" and C-7 of apigenin. The isolated proanthocyanidins have high antioxidant activities, and these compounds are probably responsible for the gastroprotective effect of the extract.
Descrição
Palavras-chave
Idioma
Inglês
Citação
Journal Of Natural Products. Washington: Amer Chemical Soc, v. 78, n. 1, p. 77-84, 2015.
