Detection of hormones in surface and drinking water in Brazil by LC-ESI-MS/MS and ecotoxicological assessment with Daphnia magna
Nenhuma Miniatura disponível
Data
2015-06-01
Autores
Torres, Nadia Hortense
Aguiar, Mario Mamede
Romanholo Ferreira, Luiz Fernando
Pine Américo, Juliana Heloisa [UNESP]
Machado, Angela Maria [UNESP]
Cavalcanti, Eliane Bezerra
Tornisielo, Valdemar Luiz
Título da Revista
ISSN da Revista
Título de Volume
Editor
Springer
Resumo
The growing use of pharmaceutical drug is mainly due to several diseases in human and in animal husbandry. As these drugs are discharged into waterways via wastewater, they cause a major impact on the environment. Many of these drugs are hormones; in which even at low concentrations can alter metabolic and physiological functions in many organisms. Hormones were found in surface water, groundwater, soil, and sediment at concentrations from nanograms to milligrams per liter of volume-quantities known to cause changes in the endocrine system of aquatic organisms. This study aimed to develop a methodology for hormone detection (estriol, estrone, 17 beta-estradiol, 17 alpha-ethinylestradiol, progesterone, and testosterone) on surface and treated water samples. Sample toxicity was assessed by ecotoxicology tests using Daphnia magna. A liquid chromatograph coupled to a mass spectrometer with an electrospray ionization source (LC-ESI-MS/ MS) was used for the analysis. The results showed that samples were contaminated by the hormones estriol, estrone, progesterone, 17 beta-estradiol, and 17 alpha-ethinylestradiol during the sampling period, and the highest concentrations measured were 90, 28, 26, 137, and 194 ng.L-1, respectively. This indicates the inflow of sewage containing these hormones at some points in the Piracicaba River in the State of Sao Paulo-Brazil. Results indicated little toxicity of the hormone estriol in D. magna, indicating that chronic studies with this microcrustacean are necessary.
Descrição
Palavras-chave
Surface water, Liquid chromatography, Hormones, Mass spectrometer, Environmental contamination, Aquatic environment
Como citar
Environmental Monitoring And Assessment. Dordrecht: Springer, v. 187, n. 379, p. 1-13, 2015.