Septic arthritis: immunopathogenesis, experimental models and therapy
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Data
2014-06-06
Autores
Colavite, Priscila Maria
Sartori, Alexandrina
Título da Revista
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Editor
Centro de Estudos de Venenos e Animais Peçonhentos - CEVAP, Universidade Estadual Paulista - UNESP
Resumo
Septic arthritis is an inflammatory disease of the joints that is started by an infection whose most common agent is Staphylococcus aureus. In this review we discuss some of the most arthritogenic bacterial factors and the contribution of innate and specific immune mechanisms to joint destruction. Special emphasis is given to the induction of experimental arthritis by S. aureus in mice. The improvement of therapy by association of antibiotics with down-modulation of immunity is also included.
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Palavras-chave
Septic arthritis, Staphylococcus aureus, Mice
Como citar
Journal of Venomous Animals and Toxins including Tropical Diseases. Centro de Estudos de Venenos e Animais Peçonhentos - CEVAP, Universidade Estadual Paulista - UNESP, v. 20, p. 01-08, 2014.