Effectiveness of a toothpaste with low fluoride content combined with trimetaphosphate on dental biofilm and enamel demineralization in situ

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Data

2015

Autores

Takeshita, Eliana Mitsue [UNESP]
Danelon, Marcelle [UNESP]
Castro, Luciene Pereira de [UNESP]
Sassaki, Kikue Takebayashi [UNESP]
Delbem, Alberto Carlos Botazzo [UNESP]

Título da Revista

ISSN da Revista

Título de Volume

Editor

S. Karger AG, Basel

Resumo

The aim of the present study was to evaluate in situ whether a toothpaste with low fluoride associated with sodium trimetaphosphate (TMP) would provide similar effect to that of a 1,100 ppm F toothpaste. This crossover double-blind study consisted of 4 phases (14 days each), during which 10 volunteers wore oral appliances containing 4 enamel bovine blocks. The cariogenic challenge was performed by the application of a 20% sucrose solution (6×/day). The toothpaste treatments (2×/day) were: placebo, 500 ppm F, 500 ppm F plus 1% TMP, and 1,100 ppm F. At the end, enamel mineral loss and biofilm composition were analyzed. The toothpaste with 500 ppm F plus 1% TMP showed the lowest mineral loss (p < 0.05). Regarding the fluoride and calcium concentrations in the enamel and in the biofilm, there were no significant differences between 500 ppm F plus 1% TMP, and 1,100 ppm F toothpastes (p > 0.569), but they were significantly different when compared to toothpaste with 500 ppm F (p < 0.050). The addition of 1% TMP to a low-fluoride toothpaste reduces enamel demineralization in situ similar to a 1,100 ppm F toothpaste.

Descrição

Palavras-chave

Biofilm, Fluoride, Ionic strength, Polyphosphates, Tooth demineralization

Como citar

Caries Research, v. 49, n. 4, p. 394-400, 2015.