Artigos - Materiais Odontológicos e Prótese - FOA

URI Permanente para esta coleção

https://hdl.handle.net/11449/15168

Navegar

Agora exibindo 1 - 20 de 991

Analgesic potential of transdermal nicotine patch in surgery: a systematic review and meta-analysis of randomised placebo-controlled trials
(2023-05-01) da Silva Barbirato, Davi; de Melo Vasconcelos, Amanda Freire; Dantas de Moraes, Sandra Lúcia; Pellizzer, Eduardo Piza [UNESP]; do Egito Vasconcelos, Belmiro Cavalcanti; University of Pernambuco (UPE); Universidade Federal de Pernambuco (UFPE); Universidade Estadual Paulista (UNESP); Oral and Maxillofacial Surgery at Hospital da Restauração
Objectives: We aimed (1) to systematically review the efficacy of transdermal nicotine patches (NP) for postoperative analgesia, (2) to establish the current quality of evidence and assist clinical decision-making on the subject, and (3) to identify methodological limitations and the need for more well-designed studies. Materials and methods: We searched six electronic databases, protocol records, and other sources without date or language restriction until March 2022. To develop the search strategy, we formulated a clinical question by using the PICOD method. Eligibility criteria included randomised placebo-controlled trials on the analgesic potential of NP for surgical procedures. This systematic review followed the PRISMA 2020 statement, and we registered the protocol in PROSPERO (#CRD42020205956). Results: We included 10 randomised placebo-controlled trials (535 patients). The NP administered before induction of anaesthesia and at beginning of surgery reduced the pain immediately after surgery (−0.38; 95% confidence interval [CI]: −0.73 to −0.02), and 6 h (−0.34; 95% CI: −0.68 to −0.01), 12 h (−0.43; 95% CI: −0.71 to −0.15) and 24 h (−0.35; 95%CI: −0.59 to −0.10) after surgery, compared with the placebo patch (PP) group. Sensitivity testing suggests that opioid use could underestimate NP analgesia. Late demand for the first analgesic and consumption of rescue analgesics tended to be lower in the NP group. Conclusions: The current findings suggest, with low certainty of evidence, the analgesic potential of NP for surgical procedures. Clinical relevance: Perioperative use of NP significantly improved postoperative pain, even when opioids were administered or prescribed. Nevertheless, the clinical relevance should be interpreted with caution, owing to the effect sizes of the summary measures and methodological issues. The analgesic potential of NP as an adjuvant therapy to regulate pain and acute inflammation may offer certain clinical advantages, thus warranting further investigation.
Mechanical properties and accuracy of removable partial denture frameworks fabricated by digital and conventional techniques: A systematic review
(2023-01-01) Souza Curinga, Míria Rafaelli; Claudino Ribeiro, Anne Kaline; de Moraes, Sandra Lúcia Dantas; do Egito Vasconcelos, Belmiro Cavalcanti; da Fonte Porto Carreiro, Adriana; Pellizzer, Eduardo Piza [UNESP]; Federal University of Rio Grande do Norte (UFRN); University of Pernambuco (UPE); Universidade Estadual Paulista (UNESP)
Statement of problem: Providing a removable partial denture (RPD) can be a complex, time-consuming, and error-prone procedure. Computer-aided design and computer-aided manufacturing (CAD-CAM) techniques have shown promising clinical outcomes; however, the influence of manufacturing techniques on the properties of RPD components is unclear. Purpose: The purpose of this systematic review was to determine the accuracy and mechanical properties of RPD components fabricated with conventional and digital methods. Material and methods: This study followed the guidelines of the Preferred Reporting Items for Systematic Review and Meta-analyses (PRISMA) and was registered on the international prospective register of systematic reviews (PROSPERO) database (CRD42022353993). An electronic search was conducted on PubMed/MEDLINE, Scopus, Web of Science, and the Cochrane Library in August 2022. Only in vitro studies comparing the digital with the lost-wax casting technique were included. The quality of the studies was assessed by using the methodological index for nonrandomized studies (MINORS) scale. Results: Of the 17 selected studies, 5 evaluated the accuracy of RPD components as well as the mechanical properties, 5 studies evaluated only the component accuracy, and another 7 evaluated only the mechanical properties. The accuracy was similar regardless of the technique, with discrepancies within clinically acceptable values (50 to 426.3 μm). The surface roughness was higher for 3D-printed clasps and lower for milled clasps (P<.05). The metal alloy significantly influenced the porosity, with the highest number of pores obtained by casting for Ti clasps and by rapid prototyping for Co-Cr clasps. Conclusions: In vitro studies showed that the digital technique provided similar accuracy to that of the conventional technique within a clinically acceptable range. The manufacturing technique influenced the mechanical properties of RPD components.
Biomechanical performance of three fiberglass post cementation techniques: Imaging, in vitro, and in silico analysis
(2023-01-01) Hoshino, Isis Almela Endo [UNESP]; Dos Santos, Paulo Henrique [UNESP]; Briso, Andre Luiz Fraga [UNESP]; Sundfeld, Renato Herman [UNESP]; Yamaguchi, Satoshi; Rocha, Eduardo Passos [UNESP]; Anchieta, Rodolfo Bruniera [UNESP]; Universidade Estadual Paulista (UNESP); Osaka University Graduate School of Dentistry; Centro Universitario do Norte Paulista-UNIPOS UNORP
Purpose: The structural integrity of the resin cement layer, the bond strength, and the biomechanical behavior of different fiberglass post cementation techniques were evaluated. Methods: Thirty-three bovine incisors were divided into three groups (n = 11): conventional fiberglass post (CFP), conventional fiberglass post in flared root canals (CFL), and relined fiberglass post (RFP). Six specimens from each group were submitted for high-resolution microcomputed tomography (μCT) to evaluate the integrity and presence/volume of voids at the resin cement layer. Finite element analysis (FEA) of two three-dimensional (3D) models of each group were conducted, one considered ideal (without interface defects) and another containing the conditions identified in the μCT analysis. Push-out bond strength tests were conducted for all specimens. Results: The CFL group had the greatest mean values of void (Thirds cervical: 73.67; middle: 95.67; apical: 47.33) and gap concentration (Thirds cervical: 14.67; middle: 15.83; apical: 8.33) compared with CFP and RFP. A significant difference in bond strength was observed between the cervical (1.33 MPa) and middle thirds (1.85 MPa) compared with the apical third (4.85 MPa) of the CFL. A significant difference was observed in the bond strength in the CFL (1.33 MPa) and RFP (3.29 MPa) in the cervical third, which were statistically similar to the bond strength of the CFP. The tensile stress distributions were similar in most structures, localized in the cervical region on the lingual surface. Conclusions: Structural defects in the interface layer might influence the bond strength and biomechanical behavior under the different fiberglass post cementations.
Effect of glaze and chlorhexidine on physical and mechanical properties of bis-acryl resin: An in situ study
(2022-07-01) Commar, Betina Chairelo [UNESP]; Danelon, Marcelle [UNESP]; Panitente, Paulo Augusto [UNESP]; Silva, Emily Vivianne Freitas Da [UNESP]; Bitencourt, Sandro Basso [UNESP]; Barão, Valentim Adelino Ricrdo; Neto, Clóvis Lamartine De Moraes Melo [UNESP]; Goiato, Marcelo Coelho [UNESP]; Santos, Daniela Micheline Dos [UNESP]; Universidade Estadual Paulista (UNESP); Universidade Estadual de Campinas (UNICAMP)
BACKGROUND: Temporary prosthesis protects the oral tissues, in addition to providing aesthetic look and masticatory function until a definitive prosthesis is manufactured. OBJECTIVES: To evaluate the effect of glaze and 0.12% chlorhexidine (CHX) on the physical and mechanical properties of bis-acryl, and to evaluate the antimicrobial efficacy of CHX. MATERIAL AND METHODS: Eighty specimens of bis-acryl resin were made. Over 40 of them the glaze was applied. One specimen with and 1 specimen without glaze were placed in niches of an appliance manufactured for each patient. Each of the 20 volunteers received 2 devices. Initially, the volunteers used one device and treated it with sucrose for 7 days (control), and later they used the other device and treated it with sucrose and CHX for 7 days (test). Color, microhardness, roughness, surface energy, and insoluble extracellular polysaccharides (EPS) tests were performed. All results were submitted to the Tukey's test, with the exception of the EPS results, which were submitted to the Student's t test. RESULTS: The ΔE00 of the unglazed control group was significantly higher than that of the unglazed test group. In all groups, a significant decrease in microhardness occurred over time. At both times, the glaze significantly increased the microhardness of the specimens (in all the glazed groups). At the final time, the test glaze group showed significantly higher microhardness compared with the control glaze group. Roughness in the groups without glaze increased significantly with CHX treatment over time. At both times, the glaze generated a significant reduction in roughness in the control and test groups. There was a significant reduction in surface energy over time in all groups. In most comparisons, the glazed groups showed significantly higher surface energy values compared with the unglazed control group. At the final time point, the unglazed test group showed a significantly higher surface energy value than the unglazed control group; and the glazed test group showed a significantly higher surface energy value compared with the glazed control group. The resins that received CHX had a significantly lower amount of biofilm. CONCLUSIONS: Color values were clinically acceptable in all tested groups. At both time points, the roughness values were clinically acceptable only in the glazed groups. Glaze increased the microhardness of the specimens. Microhardness and surface energy were reduced over time in all groups. Chlorhexidine can help prevent microhardness degradation. Glaze and CHX can increase surface energy. Chlorhexidine reduced the amount of bacterial biofilm.
Biomaterial engineering surface to control polymicrobial dental implant-related infections: focusing on disease modulating factors and coatings development
(2023-01-01) Malheiros, Samuel S.; Nagay, Bruna E.; Bertolini, Martinna M.; de Avila, Erica D. [UNESP]; Shibli, Jamil A.; Souza, João Gabriel S.; Barão, Valentim A. R.; Universidade Estadual de Campinas (UNICAMP); University of Pittsburgh; Universidade Estadual Paulista (UNESP); Guarulhos University; Dental Science School (Faculdade de Ciências Odontológicas - FCO)
Introduction: Peri-implantitis is the leading cause of dental implant loss and is initiated by a polymicrobial dysbiotic biofilm formation on the implant surface. The destruction of peri-implant tissue by the host immune response and the low effectiveness of surgical or non-surgical treatments highlight the need for new strategies to prevent, modulate and/or eliminate biofilm formation on the implant surface. Currently, several surface modifications have been proposed using biomolecules, ions, antimicrobial agents, and topography alterations. Areas covered: Initially, this review provides an overview of the etiopathogenesis and host- and material-dependent modulating factors of peri-implant disease. In addition, a critical discussion about the antimicrobial surface modification mechanisms and techniques employed to modify the titanium implant material is provided. Finally, we also considered the future perspectives on the development of antimicrobial surfaces to narrow the bridge between idea and product and favor the clinical application possibility. Expert opinion: Antimicrobial surface modifications have demonstrated effective results; however, there is no consensus about the best modification strategy and in-depth information on the safety and longevity of the antimicrobial effect. Modified surfaces display recurring challenges such as short-term effectiveness, the burst release of drugs, cytotoxicity, and lack of reusability. Stimulus-responsive surfaces seem to be a promising strategy for a controlled and precise antimicrobial effect, and future research should focus on this technology and study it from models that better mimic clinical conditions.
Survival of osseointegrated implants: a 10-year retrospective study
(2023-03-01) Penitente, P. A. [UNESP]; do Vale Souza, J. P. [UNESP]; dos Santos, D. M. [UNESP]; Brunetto, J. L. [UNESP]; de Moraes Melo Neto, C. L. [UNESP]; Bueno Carlini Bittencourt, A. B. [UNESP]; de Sousa Ervolino, I. C. [UNESP]; Goiato, M. C. [UNESP]; Universidade Estadual Paulista (UNESP)
Introduction. New techniques, surgical protocols, dental implant designs, and prosthetic rehabilitation have been used in dentistry, most of which have yielded good results in the literature. This retrospective survey assessed the clinical results of patients rehabilitated with dental implants between January 2011 and December 2021. Load protocols (immediate and conventional), types of connections of the installed implants, external hexagon (EH), and cone morse (MC) were evaluated. Material and methods. Two evaluators were selected and calibrated to perform the analyses. The inclusion criteria were records with complete and legible information of patients rehabilitated with dental implants who were followed for at least 1 year after rehabilitation. The medical records were divided into two groups, G1 (implants with conventional load) and G2 (implants with immediate load), and further subdivided according to implant type. Information about the rehabilitation failures was noted and descriptive statistics of the results were obtained. Results. Among the 432 evaluated medical records of patients rehabilitated with implants, the study included 319 records: 223 from women and 96 from men, aged 20–79 years. In total, data were available on 1,227 implants with dimensions of 10–13 mm and diameters of 3.75–4 mm. The G1 (n=1.188) survival rates were 94.95% for EH implants and 99.5% for MC implants. In G2 (n=39), the survival rates were 93.75% for EH implants and 91.3% for MC implants. The implant survival rates were relatively high among all groups evaluated; however, the discrepancy between the number of implants in the groups may compromise the comparison between them. Understanding and respecting the biomechanical and technical principles of each protocol was the main factor influencing the success of rehabilitation. Conclusion. The results of this study showed that, according to medical records, rehabilitation with dental implants showed excellent results regardless of the connection type (EH or MC) or loading protocol (conventional or immediate). The two loading protocols and two connection types had excellent results and scientific support. Therefore, the choice should be based on the clinical needs of each patient.
Influence of thickness and degree of opacity of lithium disilicate on the degree of conversion and bond strength of resin cements
(2023-07-01) Queiroz, Mariana Elias [UNESP]; Maluly-Proni, Ana Teresa [UNESP]; Tsutsumi, Mariana Sati Cantalejo [UNESP]; Dallazen, Eduardo [UNESP]; de Castro-Hoshino, Lidiane Vizioli; de Souza, Monique; Baesso, Mauro Luciano; dos Santos, Paulo Henrique [UNESP]; Universidade Estadual Paulista (UNESP); Universidade Estadual de Maringá (UEM); Faculty of Dentistry – UofT
The aim of this study was to evaluate the influence of various opacities and thicknesses of lithium disilicate on the degree of conversion (DC) of two resin cements and on their bond strength (BS) to the ceramic. Two hundred and forty ceramic samples of lithium disilicate with high translucency (HT), low translucency (LT), and medium opacity (MO) were obtained from IPS e. max CAD in five different thicknesses. Light-cured and dual-cured resin cements were used for DC (n = 9) and BS (n = 8). Cement samples were light-cured under ceramic samples and analyzed using a Raman confocal spectrometer to determine the DC. For BS, resin cement cylinders were fabricated using ceramic samples which were thsen subjected to a microshear bond strength test. The mean values were provided for statistical analysis. The increase in thickness resulted in a decrease in DC for both cements under all experimental conditions, but only affected the BS of the light-cured cement for the MO ceramic. Comparing the opacities, the most translucent ceramics with particular thicknesses exhibited higher DC values than the less translucent ceramics. The LT and MO ceramics with certain thicknesses exhibited the highest BS values than the HT. The dual-cured cement generally showed highest values in both analyses than the light-cured cement. A thicker and more opaque ceramic material can reduce the DC of the cement. The BS decreases with the increasing thickness of the more-opaque ceramics.
Evaluation of the mechanical properties of different materials for manufacturing occlusal splints
(2023-01-01) Guimaraes, Danielly Mendonça; Campaner, Marcio [UNESP]; dos Santos, Rodrigo Wendel; Pesqueira, Aldieris Alves; de Medeiros, Rodrigo Antonio; Universidade de Brasília (UnB); Universidade Estadual Paulista (UNESP); private practice
This study aimed to compare the mechanical properties of various occlusal plate materials by analyzing surface roughness, Knoop microhardness, flexural strength, and modulus of elasticity. Fifty samples were prepared and classified as SC (self-curing acrylic resin), WB (heat-cured acrylic resin), ME (acrylic resin polymerized by microwave energy), P (resin print), and M (polymethylmethacrylate polymer block for computer-aided design/computer-aided manufacturing). The data were analyzed using a one-way analysis of variance and Tukey’s honestly significant difference test. Surface roughness was the same in all groups. The surface hardness of group M was statistically superior. The samples from groups P and M had higher flexural strength than other samples. The modulus of elasticity of group SC was statistically lower than that of other groups. The mechanical properties of the materials used to make the occlusal plates differed, and group M achieved the best results in all analyses. Therefore, clinicians must consider the material used to manufacture long-lasting and efficient occlusal splints.
Toxicity and Anti-Inflammatory Effects of Agave sisalana Extract Derived from Agroindustrial Residue
(2023-04-01) Costa, Luisa Taynara Silvério da [UNESP]; Fracasso, Julia Amanda Rodrigues [UNESP]; Guarnier, Lucas Pires; Brito, Gustavo Reis de [UNESP]; Fumis, Daniel Baldini [UNESP]; Camargo Bittencourt, Renata Aparecida de; Guiotti, Aimée Maria [UNESP]; Barros Barbosa, Débora de [UNESP]; Camargo, Isabel Cristina Cherici [UNESP]; Souza, Edislane Barreiros de [UNESP]; Oliva Neto, Pedro de [UNESP]; Santos, Lucinéia dos [UNESP]; Universidade Estadual Paulista (UNESP); Universidade de São Paulo (USP)
Background: In several countries, the leaf juice of Agave sisalana (also known as sisal) is widely used topically, especially as an antiseptic, and orally for the treatment of different pathologies. However, in Brazil, which is the largest producer of Agave sisalana, its residue, which represents the majority of its weight, has been thrown away. For this reason, the determination of the pharmacological and toxicological potentials of sisal residue and its possible therapeutic use is seen as a way to contribute to the sustainable development and social promotion of the largest producer of sisal in Brazil, the interior of Bahia State, which is among the poorest areas in the country. Given the scarcity of available scientific studies on the pharmacological and toxicological properties of sisal residue juice, this study aimed to promote the acid hydrolysis of this juice to potentiate the anti-inflammatory effect already described in the literature. Furthermore, it aimed to evaluate the toxicological profile of the hydrolyzed extract (EAH) and to determine its acute toxicity, as well as its side effects on the reproductive aspects of rats. Method: The anti-inflammatory effect of EAH was evaluated in vitro using the induction of hemolysis by hypotonic solution and in vivo in rats using the carrageenan-induced paw edema test and the xylene-induced ear edema test. The acute toxicity, resulting from a single-dose administration, was investigated for some manifestation of toxic symptoms related to motor control and consciousness in rats. At a concentration of 100 mg/kg, by repeated doses, the reproductive toxicity effects of EAH in rats were assessed. Results: In vitro anti-inflammatory activity was positive using the human red blood cell membrane stabilization method. In both in vivo tests used to assess the anti-inflammatory activity, EAH (at three doses) significantly inhibited edema when compared to the control group. At a dose of 50 mg/kg, EAH exhibited a greater effect than indomethacin, a nonsteroidal anti-inflammatory drug with known activity. In vivo toxicological studies have shown that EAH does not present toxic effects when administered orally in a single dose, up to 1000 mg/kg. Finally, EAH promoted a gonadotoxic effect and increased the embryonic mortality rate after implantation. Conclusions: It is suggested that the anti-edematogenic effect of the acid hydrolysis extract from sisal juice is due to the high concentration of steroidal sapogenins. Therefore, this extract can be considered a potential new anti-inflammatory or even an important sapogenin source for the development of steroidal glucocorticoids. However, further studies are needed to elucidate the chemical composition of sisal juice. Regarding toxicology studies, EAH did not show cytotoxic and clastogenic potentials, but it presented a powerful reproductive toxic effect in rats.
Do dental implants placed in patients with osteoporosis have higher risks of failure and marginal bone loss compared to those in healthy patients? A systematic review with meta-analysis
(2023-01-01) Lemos, Cleidiel Aparecido Araujo; de Oliveira, Andreza Soares; Faé, Daniele Sorgatto; Oliveira, Hiskell Francine Fernandes e [UNESP]; Del Rei Daltro Rosa, Cleber Davi [UNESP]; Bento, Victor Augusto Alves [UNESP]; Verri, Fellippo Ramos [UNESP]; Pellizzer, Eduardo Piza [UNESP]; Federal University of Juiz de Fora (UFJF); Universidade Estadual Paulista (UNESP)
Purpose: This systematic review and meta-analysis aimed to compare the dental implant survival rate and marginal bone loss between patients with and without osteoporosis. Materials and methods: This systematic review was registered in PROSPERO (CRD42022356377). A systematic search was performed using five databases: MEDLINE/PubMed, Web of Science, Scopus, Embase, and ProQuest for articles published up to July 2022. Additional searches in ClinicalTrials.gov and the reference lists of included studies were performed. The eligibility criteria comprised observational studies with a direct comparison between patients with and without osteoporosis, with a minimum follow-up of 1 year and 10 implants placed in each group, which consider data analysis based on implant level, without restrictions on period or language of publication. The meta-analysis was performed using RevMan 5.4 program. Risk of bias analysis of the included studies was performed using the Newcastle–Ottawa scale (NOS). Results: Twelve studies met the eligibility criteria, totaling 1132 patients with a mean age range from 54 to 76.6 years. Most of the included patients were women (73.6%). A total of 3505 implants were evaluated—983 in patients with osteoporosis and 2522 in patients without osteoporosis. The meta-analysis indicated no difference in implant survival rates between patients with and without osteoporosis (OR, 1.78; 95% confidence interval [CI], 0.86–3.70; P = 0.12). However, significant bone loss was observed around dental implants placed in patients with osteoporosis (SMD, 0.71 mm; 95% CI, 0.06–0.87 mm). The NOS indicated a low risk of bias in the studies included. However, the certainty of the evidence was classified as very low and low for implant survival rates and bone loss, respectively. Conclusion: According to the limitations of the present review, the data suggest that dental implants are a viable treatment option for the rehabilitation of patients with osteoporosis. However, clinical care by professionals is necessary to ensure the maintenance of peri-implant bone stability, as these patients may be susceptible to increased bone loss.
Does the use of conventional complete dentures influence taste perception? A systematic review
(2023-01-01) Avelino, Maria Eduarda Lemos; Vila-Nova, Taciana Emília Leite; Costa, Rayanna Thayse Florêncio; Pellizzer, Eduardo Piza [UNESP]; Vasconcelos, Belmiro Cavalcanti do Egito; Moraes, Sandra Lúcia Dantas; University of Pernambuco (UPE); Faculty of Dentistry; Universidade Estadual Paulista (UNESP)
Statement of problem: Although conventional complete dentures are widely used, a systematic review of their influence on wearers' taste perception is lacking. Purpose: The purpose of this systematic review was to determine whether conventional complete dentures influence the taste perception of edentulous patients. Material and methods: This systematic review was registered in the International Prospective Register of Systematic Reviews (PROSPERO) (CRD42022341567), and the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) were followed. The guiding question was: “Does the use of complete dentures influence the taste perception of edentulous patients?” Two reviewers searched articles in the PubMed/MEDLINE, Scopus, Cochrane Library, and https://clinicaltrials.gov databases up to June 2022. The risk of bias in each study was assessed using the risk of bias in nonrandomized studies of interventions and the risk of bias based on the Cochrane risk of bias tool for randomized trials. The certainty of evidence was assessed using grading of recommendations, assessment, development, and evaluation (GRADE). Results: A total of 883 articles were found with the search, and 7 were included in this review. Various changes in taste perception were identified in some of these studies. Conclusions: The use of conventional complete dentures can influence the perception of the 4 primary tastes (sweet, salty, sour, and bitter) of edentulous patients, which may negatively interfere with the perception of flavor.
Biomechanical influence of narrow-diameter implants placed at the crestal and subcrestal level in the maxillary anterior region. A 3D finite element analysis
(2023-01-01) Cruz, Ronaldo S. [UNESP]; Fernandes e Oliveira, Hiskell Francine [UNESP]; Lemos, Cleidiel Aparecido Araújo; de Souza Batista, Victor Eduardo; Capalbo da Silva, Rodrigo [UNESP]; Verri, Fellippo R. [UNESP]; Universidade Estadual Paulista (UNESP); Federal University of Juiz de Fora (UFJF); The University of Western São Paulo (UNOESTE)
Purpose: To evaluate the tendency of movement, stress distribution, and microstrain of single-unit crowns in simulated cortical and trabecular bone, implants, and prosthetic components of narrow-diameter implants with different lengths placed at the crestal and subcrestal levels in the maxillary anterior region using 3D finite element analysis (FEA). Materials and methods: Six 3D models were simulated using Invesalius 3.0, Rhinoceros 4.0, and SolidWorks software. Each model simulated the right anterior maxillary region including a Morse taper implant of Ø2.9 mm with different lengths (7, 10, and 13 mm) placed at the crestal and subcrestal level and supporting a cement-retained monolithic single crown in the area of tooth 12. The FEA was performed using ANSYS 19.2. The simulated applied force was 178 N at 0°, 30°, and 60°. The results were analyzed using maps of displacement, von Mises (vM) stress, maximum principal stress, and microstrain. Results: Models with implants at the subcrestal level showed greater displacement. vM stress increased in the implant and prosthetic components when implants were placed at the subcrestal level compared with the crestal level; the length of the implants had a low influence on the stress distribution. Higher stress and strain concentrations were observed in the cortical bone of the subcrestal placement, independent of implant length. Non-axial loading influenced the increased stress and strain in all the evaluated structures. Conclusions: Narrow-diameter implants positioned at the crestal level showed a more favorable biomechanical behavior for simulated cortical bone, implants, and prosthetic components. Implant length had a smaller influence on stress or strain distribution than the other variables.
In vitro study on how photodynamic therapy and calcium hydroxide medication influence adhesive interface properties of glass-fiber posts to intraradicular dentin
(2023-05-01) Strazzi-Sahyon, Henrico Badaoui [UNESP]; Banci, Henrique Augusto [UNESP]; Melo, Fernanda Santos de [UNESP]; Soares, Lucas Silva; Spin-Neto, Rubens; Duarte, Marco Antonio Hungaro; Cintra, Luciano Tavares Angelo [UNESP]; dos Santos, Paulo Henrique [UNESP]; Sivieri-Araujo, Gustavo [UNESP]; Universidade Estadual Paulista (UNESP); Universidade de São Paulo (USP); Centro Paula Souza Araçatuba; Aarhus University; Faculty of Dentistry
Purpose: This in vitro study evaluated the influence of antimicrobial photodynamic therapy (aPDT), using methylene blue (MB) as photosensitizer (PS) and calcium hydroxide (CH) as intracanal medication on adhesive bond strength, sealing, and integrity of the luting interface of glass-fiber posts to different thirds of endodontically treated root canal dentin. Material and methods: 102 incisors were sorted into 6 groups: a negative control irrigated with deionized water; a positive control irrigated with deionized water and filled with CH; CH + MB 50 mg/L without laser radiation; CH + MB 100 mg/L without laser radiation; CH + MB 50 mg/L radiated by red laser; and CH + MB 100 mg/L radiated by red laser. Push-out bond strength (n = 8), adhesive interface sealing (n = 3), and volume and quantification of voids (n = 6) were assessed using a universal testing machine, confocal laser scanning microscope, and computerized microtomography, respectively. Scanning electron micrographs were obtained from representative samples to qualify the fracture patterns. Push-out bond strength and adhesive interface integrity data were subjected to 2-way ANOVA for repeated measures followed by Tukey's test (α = 0.05). Adhesive interface sealing was evaluated by the inter-examiner Kappa test and submitted to Kruskal-Wallis and Dunns tests (α = 0.05). Results: Assessing the apical region, the positive control and MB100WA + Ca(OH)2 groups showed lower adhesive bond strength compared to the MB100A + Ca(OH)2 group (P < 0.05). The cervical third showed higher bond strength than the apical third for the positive control, MB50WA + Ca(OH)2, MB100WA + Ca(OH)2, and MB50A + Ca(OH)2 groups (P < 0.05). A prevalence of mixed failure was observed in all experimental groups. There were no statistically significant differences in adhesive interface sealing for any of the parameters assessed (P > 0.05). MB100WA + Ca(OH)2 and MB100A + Ca(OH)2 groups promoted a higher volume and quantification of voids compared to the negative control group evaluating the cervical third (P < 0.05). In general, there were no differences in the quantification of voids comparing the intraradicular thirds (P > 0.05), differently to the volume of voids in which, in general, the cervical third promoted higher values compared to the middle and apical thirds (P < 0.05). Conclusion: aPDT with methylene blue PS at 50 mg/L associated with calcium hydroxide as intracanal medication demonstrated satisfactory bond strength, sealing, and integrity of the adhesive interface at any intraradicular depth.
Evaluation of bond strength of glass and resin-ceramics with laser phototherapy: A systematic review and meta-analysis of in vitro studies
(2023-01-01) Nascimento, Victor Alves [UNESP]; Bento, Victor Augusto Alves [UNESP]; Cruz, Kevin Henrique [UNESP]; Rosa, Cleber Davi Del Rei Daltro [UNESP]; Pesqueira, Aldiéris Alves [UNESP]; Pellizzer, Eduardo Piza [UNESP]; Universidade Estadual Paulista (UNESP)
Statement of problem: Laser phototherapy has been studied as a surface treatment capable of increasing the adhesion of cement to the ceramic surface. However, the bond strength of glass and resin-ceramics after laser phototherapy is unclear. Purpose: The objective of this systematic review and meta-analysis was to compare the bond strength of glass and resin-ceramics using laser therapy and conventional hydrofluoric acid etching. Material and methods: This systematic review and meta-analysis followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and was registered in the Open Science Framework (OSF) for in vitro studies. A population, intervention, control, and outcome (PICO) question was formulated: “Does phototherapy promote better bond strength in glass and resin-ceramics than conventional hydrofluoric acid etching?” A literature search was performed in PubMed/MEDLINE, Embase, Web of Science, Scopus, Cochrane Library, and ProQuest databases up to January 2023. The Joanna Briggs Institute critical assessment guidelines for quasi-experimental studies were used for quality assessment. The meta-analysis was based on the inverse variance (IV) method (α=.05). Results: A total of 6 in vitro studies published between 2007 and 2019 with a total number of 348 specimens were included for qualitative analysis; 1 study had a positive effect. Five of the studies were included in the meta-analysis, which indicated a significant decrease for feldspathic ceramics that received laser phototherapy and lithium disilicate (P=.002; MD: −2.15; 95% CI: −3.53 to −0.77; I2=89%, P<.01) and (P<.01; MD: −2.13; 95% CI: −2.99 to −1.27; I2=82%, P<.01), respectively. Conclusions: Laser irradiation as surface etching of glass ceramics does not produce a bond strength equal to that of conventional hydrofluoric acid etching.
Effect of Processing Methods of Human Saliva on the Proteomic Profile and Protein-Mediated Biological Processes
(2023-03-03) Miranda, Luis Fernando B.; Lima, Carolina V.; Pagin, Rafaela; Costa, Raphael C.; Pereira, Marta Maria A. [UNESP]; de Avila, Erica D. [UNESP]; Bertolini, Martinna; Retamal-Valdes, Belén; Shibli, Jamil A.; Feres, Magda; Barão, Valentim A. R.; Souza, João Gabriel S.; Universidade Estadual de Campinas (UNICAMP); Universidade Federal do Paraná (UFPR); Guarulhos University (UnG); Universidade Estadual Paulista (UNESP); University of Pittsburgh; Dental Science School (Faculdade de Ciências Odontológicas - FCO)
The use of saliva as a protein source prior to microbiological and biological assays requires previous processing. However, the effect of these processing methods on the proteomic profile of saliva has not been tested. Stimulated human saliva was collected from eight healthy volunteers. Non-processed saliva was compared with 0.22 μm filtered, 0.45 μm filtered, and pasteurized saliva, by liquid chromatography-mass spectrometry. Data are available via ProteomeXchange with identifier PXD039248. The effect of processed saliva on microbial adhesion was tested using bacterial and fungus species and in biological cell behavior using HaCaT immortalized human keratinocytes. Two hundred and seventy-eight proteins were identified in non-processed saliva, of which 54 proteins (≈19%) were exclusive. Saliva processing reduced identified proteins to 222 (≈80%) for the 0.22 μm group, 219 (≈79%) for the 0.45 μm group, and 201 (≈72%) for the pasteurized saliva, compared to non-processed saliva. The proteomic profile showed similar molecular functions and biological processes. The different saliva processing methods did not alter microbial adhesion (ANOVA, p > 0.05). Interestingly, pasteurized saliva reduced keratinocyte cell viability. Saliva processing methods tested reduced the proteomic profile diversity of saliva but maintained similar molecular functions and biological processes, not interfering with microbial adhesion and cell viability, except for pasteurization, which reduced cell viability.
Is the clinical performance of internal conical connection better than internal non-conical connection for implant-supported restorations? A systematic review with meta-analysis of randomized controlled trials
(2023-06-01) Rodrigues, Vitor Venâncio Moreira; Faé, Daniele Sorgatto; Rosa, Cleber Davi Del Rei Daltro [UNESP]; Bento, Victor Augusto Alves [UNESP]; Lacerda, Mariane Floriano Lopes Santos; Pellizzer, Eduardo Piza [UNESP]; Lemos, Cleidiel Aparecido Araujo; Federal University of Juiz de Fora (UFJF); Universidade Estadual Paulista (UNESP)
Purpose: To evaluate bone loss, prosthodontics and biological complications, and implant survival rates of internal conical connections (ICC) compared with internal non-conical connection (INCC) implants. Methods: The systematic review was registered on PROSPERO (CRD42021237170). Meta-analysis was performed using standardized mean difference (SMD) for bone loss and risk ratio (RR) for implant survival and complication rates. Risk of bias analysis was evaluated using RoB 2.0, whereas the GRADE tool was used to evaluate the certainty of evidence. A systematic search of the PubMed, Web of Science, Embase, Cochrane, and ProQuest databases was performed independently by two reviewers for articles published up to March 2022. The search criteria had no language or publication date restrictions. Handsearching analysis was performed in the reference list of potential articles. Results: Twelve randomized clinical trials, including 678 patients and 1006 implants (ICC [n = 476]; INCC [n = 530]), were included. Meta-analysis revealed that ICC demonstrated a lower risk for marginal bone loss (SMD: −0.80 mm; p = 0.004) and prosthodontics complications (RR: 0.16; p = 0.01) than INCC. However, both internal connections demonstrated no significant difference in implant survival rates (RR: 0.54; p = 0.10) and biological complications (RR: 0.90; p = 0.82). The overall risk of bias revealed some concerns and a low risk of bias for most of the included studies. However, the certainty of evidence of outcomes was considered low to moderate. Conclusion: ICC may be considered a more favorable treatment option than INCC owing to greater preservation of peri-implant bone tissue and a lower probability of prosthodontics complications. However, well-conducted studies with long-term follow-up are warranted.
Are exercises with or without occlusal splints more effective in the reduction of pain in patients with temporomandibular disorders of myogenic origin? A systematic review
(2022-01-01) Batista, Jessica Fernanda de Oliveira Lima; Moraes, Sandra Lúcia Dantas; Pellizzer, Eduardo Piza [UNESP]; Vasconcelos, Belmiro Cavalcanti Do Egito; Gomes, Jéssica Marcela de Luna; Lemos, Cleidiel Aparecido Araújo; Heimer, Mônica Vilela; Faculdade de Odontologia; Universidade Estadual Paulista (UNESP); Faculdade de Odontologia da Recife; Centro Universitário FACOL-UNIFACOL; Universidade Federal de Juiz de Fora
Temporomandibular disorders (TMD) is a term used to describe a set of clinical conditions that may compromise the temporomandibular joint (TMJ) and masticatory muscles and/or associated structures, considered the most frequent cause of orofacial pain of non-dental origin. In recent years, many forms of physical therapy have been used in the treatment of TMD to reduce pain and improve the range of mandibular movement present in this impairment. Among these resources are kinesiotherapy (exercise), electrothermal and manual therapy, acupuncture, training posture, mobilizations, and biofeedback. Objectives: To determine if exercises with or without occlusal splints are effective in reducing pain in patients with temporomandibular disorders (TMD) of myogenic origin. Methodology: This systematic review was registered in the International Prospective Register of Systematic Reviews (CRD 42019134244). Controlled trials published in PubMed, Scopus, and Cochrane Library following PRISMA guidelines up to April 2022 were randomized and included. The population above 18 years, which evaluated the effectiveness of exercise with or without occlusal splints in reducing pain in patients with TMD of myogenic origin, diagnosed through the Research Diagnostic Criteria for Temporomandibular Disorders, was also included. There was no restriction on the period of publication. Cochrane risk of bias analysis was performed. Results: Of the five included articles, all showed a reduction of pain, but without significant differences between the interventions performed. Additionally, studies that evaluated the quality of life and mandibular movements showed a reduction in pain, but no significant differences between therapies. Conclusion: The analyzed studies showed no difference in the improvement of pain, quality of life, and mandibular movements between the groups that performed only exercises or the associated treatments.
Abnormal Activity of Masticatory Muscles in Patients with Diagnosis of Cerebral Palsy. A Systematic Review and Meta-Analysis of Observational Studies
(2023-01-01) Beltramin, Rafael Zaratin; Martimbianco, Ana Luiza Cabrera; Gonçalves, Marcela Leticia Leal; Rocha, Monise Mendes; Silva, Soraia Micaela; Horliana, Anna Carolina Ratto Tempestini; Santos, Elaine Marcílio; Turcio, Karina Helga [UNESP]; Mesquita-Ferrari, Raquel Agnelli; Fernandes, Kristianne Porta Santos; Motta, Lara Jansiski; Bussadori, Sandra Kalil; Universidade Nove de Julho (UNINOVE); Universidade Metropolitana de Santos (UNIMES); Universidade Estadual Paulista (UNESP)
Aims: to map and synthesize the results from studies that assessed whether individuals diagnosed with cerebral palsy (CP) have abnormal masseter and temporal muscles activation during the masticatory cycle. Methods: Six databases were searched for comparative observational studies assessing masticatory muscles activation in individuals with CP through electromyography analysis. Methodological quality was evaluated using the Joanna Briggs Critical Appraisal Checklist. Outcome data were combined in meta-analysis using the Review Manager software. Results: We included five cross-sectional studies with an overall low risk of bias. Meta-analyses showed no difference between CP and healthy individuals regarding maximum voluntary isometric contraction: right masseter (Standard mean difference [SMD] − 0.95; 95% CI −2.03 to 0.13); left masseter (SMD −0.92; 95% CI −1.93 to 0.09); right temporal (SMD −0.72; 95% CI −1.63 to 0.18); and left temporal (SMD −0.68; 95% CI −1.76 to 0.40). Electrical activity amplitude in the inactive period was superior in the CP group, and maximum bite pressure presented higher values in the control group (Mean difference [MD] − 17.38; CI 95% −26.62 to −10.15). Conclusions: Based on observational studies with a lower level of evidence, individuals with CP seem to present difficulties activating masticatory muscles. Future prospective cohort studies with rigorous methodology are still necessary to support these findings. PROSPERO register CRD42020208444.
Antimicrobial effectiveness of ultrasonic irrigation in root canal treatment: a systematic review of randomized clinical trials and meta-analysis
(2023-04-01) Chalub, Lucas Orbolato [UNESP]; Nunes, Gabriel Pereira [UNESP]; Strazzi-Sahyon, Henrico Badaoui [UNESP]; Ferrisse, Túlio Morandin [UNESP]; dos Santos, Paulo Henrique [UNESP]; Gomes-Filho, João Eduardo [UNESP]; Cintra, Luciano Tavares Angelo [UNESP]; Sivieri-Araujo, Gustavo [UNESP]; Universidade Estadual Paulista (UNESP)
Objective: The objective of this systematic review and meta-analysis (SRM) was to answer the question as to whether the use of ultrasonic irrigation (UI) results in better antimicrobial activity in root canal disinfection compared to conventional irrigation (CI). Methods: A literature search was performed in the main scientific databases, carried out until October 2021. The eligibility criteria were randomized clinical trials (RCTs). Two meta-analyses were conducted using R software with the “META” package. The mean difference (MD) and odds ratio (OR) measure of effect were calculated. The fixed effect model was applied with a 95% confidence interval. The Cochrane collaboration scale was used to assess risk of bias and the GRADE tool to assess the quality of evidence. Results: A total of 1782 records were screened, and 12 studies meeting the criteria were included in this review. A low risk of bias was observed for most domains, except allocation concealment that was considered unclear. The certainty of evidence was classified as moderate in the OR meta-analyses and low in the MD meta-analyses. Ultrasonic irrigation resulted in a better antimicrobial effect in both meta-analyses, MD 1.42 [1.60; 1.23] p < 0.0001, I2 = 80%; and OR 3.86 [1.98; 7.53] p< 0.0001, I2 = 28.7%. Conclusion: Within the limitations of this SRM, UI presented better antimicrobial efficacy than CI. Clinical Relevance: UI should be used by clinicians as it promotes better antimicrobial efficacy in patients undergoing endodontic treatment.
Impact of tilted implants for implant-supported fixed partial dentures: A systematic review with meta-analysis
(2022-01-01) Batista, Rhaslla Gonçalves; Faé, Daniele Sorgatto; Bento, Victor Augusto Alves [UNESP]; Rosa, Cléber Davi Del Rey Daltro [UNESP]; Souza Batista, Victor Eduardo de; Pellizzer, Eduardo Piza [UNESP]; Lemos, Cleidiel Aparecido Araujo; Federal University of Juiz de Fora/Campus GV (UFJF/GV); Universidade Estadual Paulista (UNESP); University of Western São Paulo (UNOESTE)
Statement of problem: The use of tilted implants has been considered a suitable option for completely edentulous patients. However, consensus on their clinical performance is lacking, specifically for partial rehabilitation. Purpose: The purpose of this systematic review and meta-analysis was to evaluate the marginal bone loss and implant survival rate of tilted implants compared with those of axial implants for implant-supported fixed partial dentures (ISFPDs). Material and methods: A systematic search of the MEDLINE/PubMed, Web of Science, Embase, Cochrane, and ProQuest databases and reference lists for articles published until May 2022 was performed by 2 independent reviewers without language or publication date restrictions. A meta-analysis was performed using the RevMan version 5.4 program. Quality assessments were performed using the Newcastle–Ottawa scale. Results: Nine studies were included, totaling 258 participants and 604 implants (269 tilted implants and 335 axial implants). No significant differences were found between the tilted and axial implants for the implant survival rate (P=.81; risk ratio: 1.14). However, higher marginal bone loss values were observed for tilted implants (P=.001; mean difference: 0.12 mm). No significant heterogeneity was observed in either analysis. Conclusions: No significant relationship was found between tilted and axial implants for ISFPD rehabilitation. However, tilted implants presented greater risks of marginal bone loss than axial implants.

Navegar

Submissões Recentes