Chemoselective condensationof beta-naphthol, dimethyl malonate, andaromatic aldehydes promoted by niobium pentachloride
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Data
2015-01-01
Autores
Bartolomeu, Aloisio de Andrade [UNESP]
Menezes, Manoel Lima de [UNESP]
Silva-Filho, Luiz Carlos da [UNESP]
Título da Revista
ISSN da Revista
Título de Volume
Editor
Taylor &francis Inc
Resumo
A multicomponent reaction of β-naphthol, dimethyl malonate, and aromatic aldehydes in the presence of NbCl5 as promoter is described. Under similar conditions, aromatic aldehydes with different substituents exhibited different behaviors than β-naphthol and dimethyl malonate. In these MCRs, 4-aryl-3,4-dihydrobenzo[f]coumarins are obtained as the major products (41–93%) and 14-aryl-14H-dibenzo[a,j]xanthenes as the minor products (1–38%).
Descrição
Palavras-chave
4-Aryl-3, 4 dihydrobenzo[f]coumarins, Chemoselective, Lewis acid, Multicomponent reactions, Niobium pentachloride
Como citar
Synthetic Communications, v. 45, n. 9, p. 1114-1126, 2015.