Evaluation of collagen-based membranes for guided bone regeneration, by three-dimensional computerized microtomography
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Data
2012-10-01
Autores
Coelho, Paulo Guilherme
Giro, Gabriela [UNESP]
Kim, Wanki
Granato, Rodrigo
Marin, Charles
Bonfante, Estevam Augusto
Bonfante, Samara
Lilin, Thomas
Suzuki, Marcelo
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Elsevier B.V.
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Objective. The aim of this study was to evaluate the use of a collagen-based membrane compared with no treatment on guided bone regeneration by 3-dimensional computerized microtomography (mu CT).Study Design. Defects were created between the mesial and distal premolar roots of the second and third premolars (beagle dogs; n = 8). A collagen-based membrane (Vitala; Osteogenics Biomedical Inc., TX, USA) was placed in one of the defects (membrane group; n = 16), and the other was left untreated (no-membrane group; n = 16). Left and right sides provided healing samples for 2 and 16 weeks. Three-dimensional bone architecture was acquired by mu CT and categorized as fully regenerated (F, bone height and width) or nonregenerated (N).Results. Chi-square tests (95% level of significance) showed that tooth did not have an effect on outcome (P = .5). Significantly higher F outcomes were observed at 16 weeks than 2 weeks (P = .008) and in membrane group than in no-membrane group (P = .008).Conclusions. The collagen-based membrane influenced bone regeneration at the furcation. (Oral Surg Oral Med Oral Pathol Oral Radiol 2012;114:437-443)
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Oral Surgery Oral Medicine Oral Pathology Oral Radiology. New York: Elsevier B.V., v. 114, n. 4, p. 437-443, 2012.