Green tea glycolic extract-loaded liquid crystal systems: development, characterization and microbiological control
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Data
2016-07-01
Autores
Bernegossi, Jessica [UNESP]
Cunha Barbosa, Raquel Maria
Rustice, Patricia Maciel
Chorilli, Marlus [UNESP]
Título da Revista
ISSN da Revista
Título de Volume
Editor
Univ Sao Paulo, Conjunto Quimicas
Resumo
Liquid crystal systems (LCSs) have interesting cosmetic applications because of their ability to increase the therapeutic efficiency and solubility of active ingredients. The aim of the present research was to develop green tea glycolic extract-loaded LCSs, to characterize and to perform microbiological control. The ternary phase diagram was constructed using polysorbate 20, silicone glycol copolymer (SGC) DC 193((R)), and distilled water with 1.5% glycolic green tea extract. The systems were characterized by polarized light microscopy. Formulations selected were characterized as transparent viscous systems and transparent liquid system indicated mesophases lamellar structure. The results of the microbiological analysis of mesophilic aerobic microorganisms (bacteria and fungi) revealed that the above formulation showed a biologic load < 10 CFU/mL in all samples. In conclusion, liquid crystalline systems that have presented formation of a lamellar mesophases were developed. Furthermore, the formulation and products tested presented the adequate microbiological quality in accordance with official recommendations.
Descrição
Palavras-chave
Camellia sinensis/glycolic extract, Liquid crystal systems/cosmetic applications, Liquid crystal systems/characterization, Liquid crystal systems/microbiological control
Como citar
Brazilian Journal Of Pharmaceutical Sciences. Sao Paulo: Univ Sao Paulo, Conjunto Quimicas, v. 52, n. 3, p. 383-390, 2016.