Publicação: Development of an oral mucosa equivalent using a porcine dermal matrix
Carregando...
Arquivos
Data
Orientador
Coorientador
Pós-graduação
Curso de graduação
Título da Revista
ISSN da Revista
Título de Volume
Editor
Tipo
Artigo
Direito de acesso
Acesso aberto
Resumo
We evaluated the suitability of a porcine acellular dermal matrix for the development of a 3-dimensional oral mucosal equivalent using an ex vivo-produced oral mucosal equivalent (EVPOME). Oral keratinocytes were seeded in a submerged model, and then in an air-liquid interphase model, using Transwell® inserts. EVPOME showed good cell viability and increased glucose consumption over time. Histological evaluation showed that stratified differentiated epithelium had formed in all matrices.
Descrição
Palavras-chave
Oral keratinocytes, oral mucosa, organotypic cell culture
Idioma
Inglês
Como citar
British Journal of Oral and Maxillofacial Surgery, v. 55, n. 3, p. 308-311, 2017.
