Development of an oral mucosa equivalent using a porcine dermal matrix
Carregando...
Data
2017-04-01
Autores
Basso, F. G. [UNESP]
Hebling, J. [UNESP]
Marcelo, C. L.
de Souza Costa, C. A. [UNESP]
Feinberg, S. E.
Título da Revista
ISSN da Revista
Título de Volume
Editor
Resumo
We evaluated the suitability of a porcine acellular dermal matrix for the development of a 3-dimensional oral mucosal equivalent using an ex vivo-produced oral mucosal equivalent (EVPOME). Oral keratinocytes were seeded in a submerged model, and then in an air-liquid interphase model, using Transwell® inserts. EVPOME showed good cell viability and increased glucose consumption over time. Histological evaluation showed that stratified differentiated epithelium had formed in all matrices.
Descrição
Palavras-chave
Oral keratinocytes, oral mucosa, organotypic cell culture
Como citar
British Journal of Oral and Maxillofacial Surgery, v. 55, n. 3, p. 308-311, 2017.