Lactone Derivatives Produced by a Phaeoacremonium sp., an Endophytic Fungus from Senna spectabilis
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2017-05-26
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Silva, Geraldo H.
Zeraik, Maria L. [UNESP]
De Oliveira, Camila M.
Teles, Helder L.
Trevisan, Henrique C. [UNESP]
Pfenning, Ludwig H.
Nicolli, Camila P.
Young, Maria C. M.
Mascarenhas, Yvonne P.
Abreu, Lucas M.
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Three new isoaigialones, A, B, and C (1-3), along with aigialone (4), were isolated from the crude EtOAc extract of a Phaeoacremonium sp., an endophytic fungus obtained from the leaves of Senna spectabilis. The structures of these compounds were elucidated based on the analysis of spectroscopic data. Compounds 2 and 4 were active against the phytopathogenic fungi Cladosporium cladosporioides and C. sphaerospermum. This is the first report of metabolites produced by an Phaeoacremonium sp., associated with S. spectabilis.
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Journal of Natural Products, v. 80, n. 5, p. 1674-1678, 2017.