Human rabies post-exposure prophylaxis relative to the disease epidemiological status
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Data
2019-01-01
Autores
Martins da Costa Andrade, Bruno Fonseca [UNESP]
Melo Andrade, Taisa Santos de
Queiroz, Luzia Helena [UNESP]
Título da Revista
ISSN da Revista
Título de Volume
Editor
Abrasco
Resumo
This study evaluated the prophylactic measures adopted after attacks by dogs and cats in the main city of Northwester Sao Paulo State, based on the technical manual for post-exposure treatment, considering the not controlled (19901996) and controlled (1997-2010) rabies status. A retrospective analysis was done using the data from the SINAN records (W64-CID10) between 1990 and 2010. In most cases, the accidents were mild (76.9%), and biting animals were healthy (75.4%); therefore, no treatment was needed in 53.3% of the cases. In 64.6% of cases, the prescribed PEP treatment was inappropriate. The most indicated PEP treatments consisted of vaccine and RIG (43.4%), and either three doses of mouse brain vaccine or two doses of cell culture vaccine (76.5%), during the not controlled and controlled rabies periods, respectively. The treatment was more appropriate and followed the technical recommendations during controlled rabies periods compared to not controlled (p < 0.0001) periods. However, excessive application of RIG and rabies vaccine was observed in both periods.
Descrição
Palavras-chave
Rabies, Animal aggression, Post-exposure prophylaxis, Immunization schedule, Dogs
Como citar
Ciencia & Saude Coletiva. Rio De Janeiro: Abrasco, v. 24, n. 1, p. 315-322, 2019.