Avaliação do ácido hialurônico reticulado, isolado e associado a vibração de corpo inteiro em cães com osteoartrose secundária à displasia coxofemoral.
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Data
2020-06-05
Autores
Martins, David José de Castro
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Universidade Estadual Paulista (Unesp)
Resumo
O presente estudo teve por objetivo avaliar o uso do ácido hialurônico reticulado, isolado e associado a Vibração de Corpo Inteiro em cães com osteoartrose secundária à displasia coxofemoral. Foram utilizados 14 cães, machos e fêmeas, de raças variadas, idade entre 43 e 134 meses e massa corpórea entre 14,5 e 29,3 kg. Os cães foram divididos, aleatoriamente em dois grupos de sete animais: Grupo 1 (G1) –infiltração intra-articular coxofemoral de AH (dose única); Grupo 2 (G2) –infiltração intra-articular coxofemoral de AH (dose única) associado as sessões de VCI, a cada 48 horas, durante 12 semanas. O AH (0,70 mL, 8,0 mg/mL) foi administrado nas articulações coxofemorais guiado por ultrassom. O protocolo de VCI iniciou com uma frequência vibratória de 30 Hz por cinco minutos, seguido de 50 Hz por cinco minutos e terminando na frequência de 30 Hz por cinco minutos, a cada 48 horas, durante 12 semanas. Foi observada diminuições significativas dos escores de claudicação e avaliação clínica ortopédica em ambos os grupos. O Pico de Força Vertical do G2 foi significamente maior que o G1. Concluiu-se que a aplicação articular coxofemoral do AH reticulado associado a Vibração de Corpo Inteiro em cães com osteoartrose secundária à displasia coxofemoral induziu melhores nos escores clínicos (dor e crepitação) e de claudicação, e nos valores de pico de força e impulso vertical.
The present study aimed to evaluate the use of intra-articular coxofemoral reticulated hyaluronic acid (HA), isolated and associated with Whole-body vibration (WBV) in dogs with osteoarthritis secondary to hip dysplasia. Fourteen dogs, males, and females, of varied breed, aged between 43 and 134 months, and body mass between 14.5 and 29.3 kg were used. The dogs were randomly divided into two groups of seven animals: Group 1 (G1) - coxofemoral HA intraarticular infiltration (single dose); Group 2 (G2) - coxofemoral HA intra-articular infiltration (single dose) associated with WBV sessions, every 48 hours, for 12 weeks. HA (0.70 mL, 8.0 mg / mL) was administered to the hip joints guided by ultrasound. The WBV protocol started with a vibrating frequency of 30 Hz for five minutes, followed by 50 Hz for five minutes and ending at a frequency of 30 Hz for five minutes, every 48 hours, for 12 weeks. Significant decreases in claudication scores and the orthopedic clinical evaluation were observed in both groups at the time-points evaluated. The Peak Vertical Force of G2 was significantly higher than that of G1. It was concluded that the intra-articular coxofemoral application of reticulated HA associated with WBV in dogs with osteoarthritis secondary to coxofemoral dysplasia induced improved the clinical scores (pain and crackling) and claudication, and better vertical peak force and vertical impulse values
The present study aimed to evaluate the use of intra-articular coxofemoral reticulated hyaluronic acid (HA), isolated and associated with Whole-body vibration (WBV) in dogs with osteoarthritis secondary to hip dysplasia. Fourteen dogs, males, and females, of varied breed, aged between 43 and 134 months, and body mass between 14.5 and 29.3 kg were used. The dogs were randomly divided into two groups of seven animals: Group 1 (G1) - coxofemoral HA intraarticular infiltration (single dose); Group 2 (G2) - coxofemoral HA intra-articular infiltration (single dose) associated with WBV sessions, every 48 hours, for 12 weeks. HA (0.70 mL, 8.0 mg / mL) was administered to the hip joints guided by ultrasound. The WBV protocol started with a vibrating frequency of 30 Hz for five minutes, followed by 50 Hz for five minutes and ending at a frequency of 30 Hz for five minutes, every 48 hours, for 12 weeks. Significant decreases in claudication scores and the orthopedic clinical evaluation were observed in both groups at the time-points evaluated. The Peak Vertical Force of G2 was significantly higher than that of G1. It was concluded that the intra-articular coxofemoral application of reticulated HA associated with WBV in dogs with osteoarthritis secondary to coxofemoral dysplasia induced improved the clinical scores (pain and crackling) and claudication, and better vertical peak force and vertical impulse values
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Palavras-chave
Vibração mecânica, Viscosuplementação, Articulação, Cinética, Plataforma vibratória, Mechanical vibration, Viscosupplementation, Articulation, Kinetics, Vibrating platform