Extranodal lymphoma in a bush dog (Speothos venaticus)-case report
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Data
2020-05-01
Autores
Carvalho, T. F.
Pessanha, A. T.
Pierezan, F.
Tinoco, H. P.
Hoffmann, A. R.
Neto, R. Torres
Amorim, R. L. [UNESP]
Paixao, T. A.
Santos, R. L.
Título da Revista
ISSN da Revista
Título de Volume
Editor
Arquivo Brasileiro Medicina Veterinaria Zootecnia
Resumo
A captive 7-year-old male bush dog (Speothos venaticus) was diagnosed with lymphoma affecting the kidneys, adrenal glands, liver, and spleen. The animal developed renal failure and was euthanized due to poor prognosis. Grossly, both kidneys were enlarged with multiple nodules. Histologically, the neoplasm was an infiltrative and poorly demarcated round cell tumor. Two morphologically distinct cell populations were observed, smaller cells with a lymphocytic morphology, and another population of larger and pleomorphic cells. Most of the smaller cell population, approximately 40% of the population within the neoplasm, were CD3 positive. Neoplastic cells were CD45, CD11d, and granzime B positive, and negative for CD20, CD79a, PAX5, CD163, and myeloperoxidase. This is the first reported case of lymphoma in a bush dog. This report demonstrated the suitability of several cell surface markers for differential diagnosis of round cell tumors in this species.
Descrição
Palavras-chave
lymphoma, immunohistochemistry, neoplasm, wildlife
Como citar
Arquivo Brasileiro De Medicina Veterinaria E Zootecnia. Minas Gerais: Arquivo Brasileiro Medicina Veterinaria Zootecnia, v. 72, n. 3, p. 754-760, 2020.