Relationship between gut microbiota, probiotics, and type 2 diabetes mellitus
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Data
2019-12-01
Autores
Salgaço, Mateus Kawata [UNESP]
Oliveira, Liliane Garcia Segura
Costa, Giselle Nobre
Bianchi, Fernanda [UNESP]
Sivieri, Katia [UNESP]
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Resumo
The worldwide prevalence of type 2 diabetes mellitus (T2DM) is constantly increasing, and it has become a major concern, with several implications for public health, economy, and social well-being. It is well-known that several factors such as lifestyle, increased intake of fat and sugar-rich foods, and host genetics can lead to T2DM. Some recent studies have suggested that the composition of the intestinal microbiota can trigger T2DM. Since then, considerable effort has been made to understand the link between the composition of intestinal microbiota and T2DM, as well as the role of probiotics in modulation of intestinal microbiota. This mini-review summarizes the major findings and discusses the close relationship between intestinal microbiota, probiotics, and T2DM.
Descrição
Palavras-chave
Chronic disease, Gut microbiota, Probiotic, Type 2 diabetes
Como citar
Applied Microbiology and Biotechnology, v. 103, n. 23-24, p. 9229-9238, 2019.