Nanotechnology as a tool for detection and treatment of arbovirus infections
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Data
2021-04-01
Autores
Duarte, Jonatas Lobato [UNESP]
Filippo, Leonardo Delello Di [UNESP]
Araujo, Victor Hugo Sousa [UNESP]
Oliveira, Anna Eliza Maciel de Faria Mota
de Araújo, Jennifer Thayanne Cavalcante [UNESP]
Silva, Flávia Benini da Rocha [UNESP]
Pinto, Mara Cristina [UNESP]
Chorilli, Marlus [UNESP]
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Resumo
Arboviruses are medically important viruses that cause high rates of infection all over the world. In addition, the severity of the symptoms and the inadequate diagnostic methods represent a challenge far beyond eradicating the vector. The lack of specific treatments for arbovirus infections reflects the imminent need for new research for safe and efficient medicines to treat these infections. Nanotechnology is an innovative approach currently used as a platform for developing new treatments, thus improving the biopharmaceutical properties of drugs. It can also be applied to the development of diagnostic devices, improving their detection capacity. The purpose of this paper is to review recent research on the use of nanotechnology for developing new treatments and detection devices for arbovirus infections. Interestingly, it was found that only a few studies report on the use of nanotechnology to treat arbovirus infections and that most of these reports focus on the fabrication of diagnostic tools. Also, some papers report on the use of nanotechnology for the development of vaccines, which in association with mosquito eradication programs could effectively reduce the high rates of infections by these viruses.
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Chikungunya, Dengue, Diagnostics devices, Drug delivery systems, Metallic nanoparticles, Vaccine, Zika
Como citar
Acta Tropica, v. 216.