Crystal Structure of Bucain, a Three-Fingered Toxin from the Venom of the Malayan Krait (Bungarus candidus)

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Data

2009-01-01

Autores

Murakami, M. T. [UNESP]
Kini, R. M.
Arni, R. K. [UNESP]

Título da Revista

ISSN da Revista

Título de Volume

Editor

Bentham Science Publ Ltd

Resumo

Bucain, a potent neurotoxin isolated from the venom of the Malayan krait (Bungarus candidus), induces paralysis and death. Its crystal structure has been determined at 2.10 angstrom resolution and based on the molecular topology and hydrophobicity profile is structurally classified as a three-fingered neurotoxin possessing a positively charged AChR-binding site.

Descrição

Palavras-chave

Bucain, Crystal structure, Bungarus candidus, three-finger alpha-neurotoxin

Como citar

Protein and Peptide Letters. Sharjah: Bentham Science Publ Ltd, v. 16, n. 12, p. 1473-1477, 2009.