Data of Nebivolol on oxidative stress parameters in hypertensive patients
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Data
2022-04-01
Autores
Barroso, Helena C. [UNESP]
Graton, Murilo E. [UNESP]
Potje, Simone R. [UNESP]
Troiano, Jéssica A. [UNESP]
Silva, Lilian X. [UNESP]
Nakamune, Ana Cláudia M.S. [UNESP]
Antoniali, Cristina [UNESP]
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Resumo
Oxidative stress is a key feature in hypertension, since reactive oxygen species are involved in all stages of cardiovascular diseases. Saliva is a body fluid that can be used to investigate alterations in the oxidative system with several specific advantages over blood. Nebivolol is a third-generation selective β1-adrenergic receptor antagonist that promotes vasodilation and has been shown to reduce oxidative stress in pre-clinical and clinical studies. The use of Nebivolol in different periods of treatment demonstrated that it is an efficient anti-hypertensive drug. We evaluated the oxidative stress biomarkers and the enzymatic and non-enzymatic antioxidant systems in saliva of hypertensive patients before and after the use of anti-hypertensive therapeutic doses of Nebivolol, since saliva can be used as an auxiliary tool to analyze parameters of oxidative stress.
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Human beings, Hypertension, Nebivolol, Oxidative stress
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Data in Brief, v. 41.