Publicação: Crystal structure of Myotoxin-II: A myotoxic phospholipase A2 - homologue from Bothrops moojeni venom
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The crystal structure of Myotoxin-II (MjTX-II), a Lys49 PLA2-homologue from Bothrops moojeni venom has been determined and refined at 2.0 Å to a crystallographic residual of 19.7% (Rfree=28.1%). MjTX-II is a dimer in the crystal, with the monomers in the asymmetric unit related by a two-fold symmetry axis running through the dimer interface. The dimers of MjTX-II and the Lys49 PLA2 from B. asper venom are similar, however the relative orientations of the monomers suggests a flexible dimer interface, which serves as a hinge between the two molecules.
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Protein and Peptide Letters, v. 4, n. 5, p. 329-334, 1997.
