Droplet counter-current chromatography of indole alkaloids from Tabernaemontana hilariana
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Data
1999-01-01
Autores
Lima Cardoso, Claudia Andrea [UNESP]
Vilegas, Wagner [UNESP]
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Resumo
This paper reports the separation of the indole alkaloids from the benzene extract of the root barks of Tabernaemontana hilariana (Apocynaceae). The crude alkaloid fraction was fractionated by droplet counter-current chromatography using a low polarity mixture (hexane:ethyl acetate:ethanol:water). Nine indole alkaloids (3-hydroxycoronaridine, coronaridine, voacangine, 3-(2-oxopropyl) coronaridine, voacangine hydroxyindolenine, ibogamine, voacangine pseudoindoxyl, coronaridine pseudoindoxyl and tabernanthine) were identified using thin layer chromatography, gas chromatography coupled with mass spectrometry and nuclear magnetic resonance spectroscopy.
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Apocynaceae, Droplet counter-current chromatography, Indole alkaloids, Tabernaemontana hilariana
Como citar
Phytochemical Analysis, v. 10, n. 2, p. 60-63, 1999.