Leukocytoclastic Vasculitis as an Extraintestinal Manifestation of Crohn's Disease
Nenhuma Miniatura disponível
Data
2021-01-01
Autores
Rocha, Thiara Barcelos [UNESP]
Garate, Ana Lorena Sousa De Vasconcelos [UNESP]
Beraldo, Rodrigo Fedatto [UNESP]
Lanças, Sean Hideo Shirata [UNESP]
Leite, Fábio Vicente [UNESP]
Quera, Rodrigo
Barros, Jaqueline Ribeiro [UNESP]
Baima, Julio Pinheiro [UNESP]
Saad-Hossne, Rogerio [UNESP]
Sassaki, Ligia Yukie [UNESP]
Título da Revista
ISSN da Revista
Título de Volume
Editor
Resumo
Cutaneous involvement is one of the most common extraintestinal manifestations of inflammatory bowel disease (IBD). More commonly, pyoderma gangrenosum and erythema nodosum are noted, but psoriasis, aphthous stomatitis, Sweet's syndrome, and vasculitis may also occur. Leukocytoclastic vasculitis (LCV) is a rare cutaneous manifestation, characterized by the appearance of palpable purpura, urticaria, and ulcer-necrotic lesions predominantly in the lower extremities that improve with immunosuppressive therapy. In this case, we report a patient with CD and LCV. We also searched the literature on the diagnosis and treatment of LCV in patients with CD. Female, 31, presented with diarrhea containing mucus and blood, abdominal pain, arthralgia, and enanthematous plaques and ulcers with a hematinic background in the lower extremities. The results of the colonoscopy were compatible with CD and skin biopsy showed signs of LCV. Systemic autoimmune disease and primary vasculitis were ruled out. The patient received treatment with a systemic corticosteroid and the skin lesions improved. Outpatient treatment with antitumor necrosis factor therapy was initiated to promote skin healing and IBD clinical remission. As LCV is a rare manifestation of IBD, it is necessary to distinguish this dermatopathy from other systemic vasculitis. The engagement of a multidisciplinary team is essential for the correct diagnosis and management.
Descrição
Palavras-chave
Case report, Crohn's disease, Extraintestinal manifestation, Inflammatory bowel disease, Leukocytoclastic vasculitis
Como citar
Case Reports in Gastroenterology, p. 825-831.