Avaliação biológica de extratos obtidos das partes aéreas e plântulas de Physalis angulata L. (solanaceae)
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Data
2021-02-24
Autores
Donadon, Maria Leonor Beneli [UNESP]
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Universidade Estadual Paulista (Unesp)
Resumo
RESUMO As plantas tornaram-se material constante em pesquisas que possam encontrar novas moléculas com atividade antimicrobiana, a fim de possibilitar inovações e trazer benefícios à população. Além do potencial natural das plantas, algumas técnicas têm sido aplicadas para aumentos de substâncias de interesse, como a elicitação de metabólitos através de aplicação de luzes em fotoperíodo controlado. O gênero Physalis tem um histórico conhecido sobre suas atividades biológicas atribuídas às fisalinas, porém ainda pouco explorado frente a fitopatógenos bem como em relação à elicitação de por luzes. O objetivo deste estudo foi avaliar a atividade antibacteriana e antifúngica dos extratos de plântulas cultivadas in vitro, elicitadas por várias luzes, e partes aéreas de Physalis angulata L. frente a microrganismos humanos e fitopatógenos.(...). Os extratos foram investigados quanto à composição fitoquímica; teor de flavonoides e fenólicos totais; atividade antioxidante; determinação da concentração inibitória mínima (CIM) para controle de fungos, bactérias, fitopatógenos e humanos; avaliação do mecanismo de ação dos extratos e toxicidade em modelo alternativo de Galleria mellonella.(...) O estudo desenvolvido demonstrou que os extratos de P. angulata tem potencial de aplicação em vários setores podendo contribuir para a geração de produtos que podem reduzir a carga de toxicidade daqueles usados atualmente.
Plants have become a constant material in research that can find new molecules with antimicrobial activity, in order to enable innovations and bring benefits to the population. In addition to the natural potential of plants, some techniques have been applied to increase substances of interest, such as the elicitation of metabolites through the application of lights in a controlled photoperiod. The genus Physalis has a known history about its biological activities attributed to physalins, but it is still little explored against phytopathogens as well as in relation to the elicitation of light. The objective of this study was to evaluate the antibacterial and antifungal activity of extracts from seedlings cultivated in vitro, elicited by various lights, and aerial parts of Physalis angulata L. against human microorganisms and phytopathogens.(...). The extracts were investigated for phytochemical composition; flavonoid and total phenolic content; antioxidant activity; determination of the minimum inhibitory concentration (MIC) for the control of fungi, bacteria, phytopathogens and humans; evaluation of the mechanism of action of the extracts and toxicity in an alternative model of Galleria mellonella.(...) The study developed showed that the extracts of P. angulata have potential for application in several sectors and may contribute to the generation of products that can reduce the toxicity load of those currently used.
Plants have become a constant material in research that can find new molecules with antimicrobial activity, in order to enable innovations and bring benefits to the population. In addition to the natural potential of plants, some techniques have been applied to increase substances of interest, such as the elicitation of metabolites through the application of lights in a controlled photoperiod. The genus Physalis has a known history about its biological activities attributed to physalins, but it is still little explored against phytopathogens as well as in relation to the elicitation of light. The objective of this study was to evaluate the antibacterial and antifungal activity of extracts from seedlings cultivated in vitro, elicited by various lights, and aerial parts of Physalis angulata L. against human microorganisms and phytopathogens.(...). The extracts were investigated for phytochemical composition; flavonoid and total phenolic content; antioxidant activity; determination of the minimum inhibitory concentration (MIC) for the control of fungi, bacteria, phytopathogens and humans; evaluation of the mechanism of action of the extracts and toxicity in an alternative model of Galleria mellonella.(...) The study developed showed that the extracts of P. angulata have potential for application in several sectors and may contribute to the generation of products that can reduce the toxicity load of those currently used.
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Palavras-chave
Physalis angulata L, Atividade antimicrobiana, Plântulas, Checkerboard, Defensivos agrícolas, Elicitação, Qualidade da luz, Physalis angulata L, Antimicrobial activity, Seedlings, Checkerboard, Pesticides, Elicitation, Quality of light