Flape do músculo esternocefálico no reparo de defeito parcial de traqueia em coelho (Oryctolagus cuniculus)
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Data
2022-05-24
Autores
Fernandes, Gustavo
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Universidade Estadual Paulista (Unesp)
Resumo
O objetivo do estudo foi avaliar, com auxílio da traqueoscopia e histopatologia, o reparo de defeito parcial da traqueia pela utilização do flape muscular, por nova técnica de avanço e padrões de suturas combinadas. Foram utilizados 16 coelhos como modelo experimental, machos, saudáveis da linhagem Nova Zelândia Branco, submetidos à criação de um defeito parcial de traqueia na região ventral do 4º ao 8º anel traqueal, com posterior reparo através de flape do músculo esternocefálico. Os animais foram distribuídos em quatro grupos, para avaliação pós-operatória pela análise clínica, traqueoscópica e histopatológica. Cada grupo foi separado de acordo com o momento das eutanásias, programadas com intervalo de sete (G7), quinze (G15), trinta (G30) e sessenta dias (G60). Um animal do G60 veio a óbito, os demais apresentaram boa recuperação cirúrgica sem alterações graves do padrão respiratório. Os principais sinais clínicos observados foram estridor e tosse. Pela traqueoscopia observou-se secreção no lúmen traqueal, granulação exuberante e estenose. Houve crescimento do epitélio respiratório ciliar no local do flape a partir de 30 dias de implantação. A reparação parcial mostrou resultados satisfatórios, devido à localização anatômica do músculo, suporte vascular próprio, manutenção estrutural e fisiológica sem alterações graves ao sistema respiratório.
The aim of the study was to evaluate, with the aid of tracheoscopy and histopathology, the repair of a partial defect of the trachea using a muscle flap, using a new advancement technique and combined suture patterns. Sixteen healthy male New Zealand White rabbits were used as an experimental model, submitted to the creation of a partial tracheal defect in the ventral region of the 4th to 8th tracheal ring, with subsequent repair through a sternocephalic muscle flap. The animals were divided into four groups for postoperative evaluation by clinical, tracheoscopic and histopathological analysis. Each group was separated according to the time of euthanasia, scheduled with an interval of seven (G7), fifteen (G15), thirty (G30) and sixty days (G60). One animal from the G60 died, the others showed good surgical recovery without serious changes in the respiratory pattern. The main clinical signs observed were stridor and cough. Tracheoscopy revealed secretion in the tracheal lumen, exuberant granulation and stenosis. Histopathological analysis showed growth of the ciliary respiratory epithelium at the flap site after 30 days of implantation. Partial repair showed satisfactory results, due to the anatomical availability of the muscle, its own vascular support and structural and physiological maintenance without serious changes to the respiratory system.
The aim of the study was to evaluate, with the aid of tracheoscopy and histopathology, the repair of a partial defect of the trachea using a muscle flap, using a new advancement technique and combined suture patterns. Sixteen healthy male New Zealand White rabbits were used as an experimental model, submitted to the creation of a partial tracheal defect in the ventral region of the 4th to 8th tracheal ring, with subsequent repair through a sternocephalic muscle flap. The animals were divided into four groups for postoperative evaluation by clinical, tracheoscopic and histopathological analysis. Each group was separated according to the time of euthanasia, scheduled with an interval of seven (G7), fifteen (G15), thirty (G30) and sixty days (G60). One animal from the G60 died, the others showed good surgical recovery without serious changes in the respiratory pattern. The main clinical signs observed were stridor and cough. Tracheoscopy revealed secretion in the tracheal lumen, exuberant granulation and stenosis. Histopathological analysis showed growth of the ciliary respiratory epithelium at the flap site after 30 days of implantation. Partial repair showed satisfactory results, due to the anatomical availability of the muscle, its own vascular support and structural and physiological maintenance without serious changes to the respiratory system.
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Palavras-chave
Cirurgia, Histopatologia, Retalho muscular, Traqueoscopia, Histopathology, Muscle flap, Surgery, Tracheoscopy, Traquéia