Injeção epidural preventiva de xilazina ou amitraz em eqüinos: efeitos clínicos e comportamentais
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Data
2009-04-01
Autores
Guirro, Erica Cristina Bueno do Prado
Ferreira, Isabella Maria Marchesini
Roberto Sobrinho, Guilherme
Valadão, Carlos Augusto Araújo [UNESP]
Título da Revista
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Editor
Universidade Federal de Santa Maria (UFSM)
Resumo
A xilazina é o fármaco agonista adrenérgico α2 mais utilizado pela via epidural de eqüinos e sabe-se que o amitraz tem ação sobre esses receptores. Assim, foram avaliados os efeitos clínicos e comportamentais causados pela injeção epidural de 0,17mg kg-1 de xilazina (GX) ou de 0,1mg kg-1 de amitraz diluído em emulsão lipídica (GA) durante 24 horas, em doze eqüinos. A freqüência cardíaca e a altura de cabeça mantiveram-se inalteradas; a freqüência respiratória aumentou de T105 a T360 no GX; a temperatura retal elevou-se de T120 a T720 em GA e de T360 a T720 em GX. Não houve diferença no tempo de latência para urinar ou defecar em ambos os grupos. em relação às alterações comportamentais, o amitraz provocou sedação (50%), ptose labial (33,4%) e palpebral (16,7%), enquanto que a xilazina promoveu ataxia (50%), sudorese perineal (33,4%), ptose palpebral (16,6%) e relaxamento do esfíncter anal (16,6%). Considera-se segura a injeção epidural de xilazina ou amitraz em eqüinos, pois as alterações clínicas e comportamentais promovidas são leves e não limitam seu uso.
Xylazine is the α2-adrenergic agonist more employed by epidural route in horses and it is known that amitraz acts on these receptors. So, clinical and behavioral effects caused by epidural injection of 0.17mg kg-1 xylazine (GX) or 0.1mg.kg-1 amitraz diluted in lipidic emulsion (GA) were evaluated in 12 horses. Heart rate and height of the head didn't change; respiratory rate increased from T105 to T360 in GX; rectal temperature increased from T120 to T720 in GA and from T360 to T720 in GX. There is no difference in latency to urine or defecate in both groups. Concerning behavioral changes, amitraz promoted sedation (50%), lip (33.4%) and eye (16.6%) dropping, while xylazine caused ataxia (50%), perineal sweating (33.4%), eye dropping (16.6%) and anal sphincter relaxation (16.6%). So, epidural injection of xylazine or amitraz was considered safe because the clinical and behavioral changes observed are subtle and don't limit its application.
Xylazine is the α2-adrenergic agonist more employed by epidural route in horses and it is known that amitraz acts on these receptors. So, clinical and behavioral effects caused by epidural injection of 0.17mg kg-1 xylazine (GX) or 0.1mg.kg-1 amitraz diluted in lipidic emulsion (GA) were evaluated in 12 horses. Heart rate and height of the head didn't change; respiratory rate increased from T105 to T360 in GX; rectal temperature increased from T120 to T720 in GA and from T360 to T720 in GX. There is no difference in latency to urine or defecate in both groups. Concerning behavioral changes, amitraz promoted sedation (50%), lip (33.4%) and eye (16.6%) dropping, while xylazine caused ataxia (50%), perineal sweating (33.4%), eye dropping (16.6%) and anal sphincter relaxation (16.6%). So, epidural injection of xylazine or amitraz was considered safe because the clinical and behavioral changes observed are subtle and don't limit its application.
Descrição
Palavras-chave
Amitraz, analgesia, epidural, Horse, xylazine, Amitraz, Analgesia, epidural, Equino, Xilazina
Como citar
Ciência Rural. Universidade Federal de Santa Maria (UFSM), v. 39, n. 2, p. 442-446, 2009.