Cadinane sesquiterpenoids of Phomopsis cassiae, an endophytic fungus associated with Cassia spectabilis (Leguminosae)
Nenhuma Miniatura disponível
Data
2006-09-01
Autores
Silva, Geraldo Humberto
Teles, Helder Lopes
Zanardi, Lisineia Maria
Marx Young, Maria Claudia
Eberlin, Marcos Nogueira
Hadad, Renato
Pfenning, Ludwig H.
Costa-Neto, Claudio Miguel
Castro-Gamboa, Ian
Bolzani, Vanderlan da Silva [UNESP]
Título da Revista
ISSN da Revista
Título de Volume
Editor
Elsevier B.V.
Resumo
Five cadinane sesquiterpenes derivatives were isolated by bioassay-guided fractionation from Phomopis cassiae, an endophytic fungus isolated from Cassia spectabilis. The structures of the two diastereoisomeric 3,9,12-trihydroxycalamenenes (1, 2); 3,12-dihydroxycalamenene (3); 3,12-dihydroxycadalene (4) and 3,11,12-trihydroxycadalene (5) were established on the basis of analyses of ID and 2D NMR and HRTOFMS experiments. Antifungal activity of the isolates was evaluated against Cladosporium sphaerospermum and Cladosporium cladosporioides, revealing 5 as the most active compound. (c) 2006 Elsevier Ltd. All rights reserved.
Descrição
Palavras-chave
Phomopsis, endophytic fungi, Cadinane Sesquiterpenes, antifungal
Como citar
Phytochemistry. Oxford: Pergamon-Elsevier B.V., v. 67, n. 17, p. 1964-1969, 2006.