Quantitative determination of cytotoxic friedo-nor-oleanane derivatives from five morphological types of Maytenus ilicifolia (Celastraceae) by reverse-phase high-performance liquid chromatography

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Data

2002-03-01

Autores

Buffa, W.
Corsino, J.
Bolzani, Vanderlan da Silva [UNESP]
Furlan, Maysa [UNESP]
Pereira, AMS
Franca, S. C.

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Editor

Wiley-Blackwell

Resumo

Five different morphological types of Maytenus ilicifolia of the same age and harvested under the same conditions showed distinct accumulations of some friedo-nor-oleananes. A rapid, sensitive and reliable reverse-phase HPLC method (employing an external standard) was used for the determination of the cytotoxic triterpenoids, 20alpha-hydroxymaytenin, 22beta-hydroxymaytenin, maytenin, celastrol and pristimerin in each of the five types. Well resolved peaks with good detection response and linearity in the range 1.0-100 mug/mL were obtained. Copyright (C) 2002 John Wiley Sons, Ltd.

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Palavras-chave

reverse-phase high-performance liquid chromatography, quantitative determination, friedo-nor-oleanane derivatives, root bark, Maytenus ilicifolia, Celastraceae, morphological types

Como citar

Phytochemical Analysis. W Sussex: John Wiley & Sons Ltd, v. 13, n. 2, p. 75-78, 2002.