nor-Lignans from the leaves of Styrax ferrugineus (Styracaceae) with antibacterial and antifungal activity
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Data
2000-11-30
Autores
Pauletti, Patricia Mendonça [UNESP]
Araújo, Angela Regina [UNESP]
Young, Maria Claudia Marx
Giesbrecht, Astréa M.
Bolzani, Vanderlan da Silva [UNESP]
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Resumo
Chemical examination of the leaves of Styrax ferrugineus yielded 5-[3'-(β-D-glucopyranosyloxy)propyl]-7-methoxy-2-(3',4'-dime-thoxyphenyl) benzofuran, along with the known nor-lignans 5-(3'-hydroxypropyl)-7-methoxy-2-(3',4'-methylenedioxyphenyl) benzofuran, 5-(3'-hydroxypropyl)-7-methoxy-2-(3',4'-dimethoxyphenyl)benzofuran, 5-[3'-(β-D-glucopyranosyloxy)propyl]-7-methoxy-2-(3', 4'-methylenedioxyphenyl)benzofuran and the lignan, dihydrodehydrodiconiferyl alcohol. All arylpropanoids isolated showed antibacterial and antifungal activities. The structures of the isolates were established by spectroscopic analysis. (C) 2000 Elsevier Science Ltd.
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Palavras-chave
Antibacterial activity, Antifungal activity, nor-Lignans, Styracaceae, Styrax ferrugineus, 5 (3'' hydroxypropyl) 7 methoxy 2 (3',4' dimethoxyphenyl)benzofuran, 5 (3'' hydroxypropyl) 7 methoxy 2 (3',4' methylenedioxyphenyl)benzofuran, 5 [3'' (beta dextro glucopyranosyloxy)propyl] 7 methoxy 2 (3',4' dimethoxyphenyl)benzofuran, 5 [3'' (beta dextro glucopyranosyloxy)propyl] 7 methoxy 2 (3',4' methylenedioxyphenyl)benzofuran, Anti Infective Agents, antifungal agent, antiinfective agent, dihydrodehydrodiconiferyl alcohol, lignan, lignan derivative, unclassified drug, angiosperm, antibacterial activity, antifungal activity, antimicrobial activity, Candida albicans, Cladosporium, Cladosporium sphaerospermum, conformation, drug isolation, drug structure, microbiological examination, nonhuman, nuclear magnetic resonance spectroscopy, plant, plant leaf, Staphylococcus aureus, structure analysis, Angiosperms, Anti-Bacterial Agents, Anti-Infective Agents, Antifungal Agents, Lignans, Magnetic Resonance Spectroscopy, Microbial Sensitivity Tests, Molecular Conformation, Plant Leaves, Magnoliophyta
Como citar
Phytochemistry, v. 55, n. 6, p. 597-601, 2000.