A new neolignan and antioxidant phenols from Nectandra grandiflora
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Data
2005-05-01
Autores
Ribeiro, Alan B. [UNESP]
Bolzani, Vanderlan da Silva [UNESP]
Yoshida, Massayoshi
Santos, Leonardo S.
Eberlin, Marcos N.
Silva, Dulce Helena Siqueira [UNESP]
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Resumo
The EtOH crude extract from the leaves of Nectandra grandiflora collected in the Atlantic Forest, Brazil, showed antioxidant activity towards β-carotene in a TLC assay. The bioassay-guided fractionation led to the isolation of protocatechuic acid and two flavonol glycosides: afzelin and quercetrin, which showed free radical scavenging activity towards DPPH (ΔA 32, 16 and 73% at 50 μmol L-1) and were compared to commercial antioxidants rutin (81% at 50 μmol L-1) and BHT (9% at 50 μmol L-1), used as standard compounds. Additionally, three inactive neolignans, including the new bicycle[3.2.1]octane neolignan 2′-oxo-piperol B were obtained and characterized by spectrometric methods. ©2005 Sociedade Brasileira de Química.
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Palavras-chave
Antioxidant, Flavonoid, Lauraceae, Nectandra grandiflora, Neolignan, Radical scavenging activity
Como citar
Journal of the Brazilian Chemical Society, v. 16, n. 3 B, p. 526-530, 2005.