Electrospray ionization mass spectrometry screening of piperidine alkaloids from Senna spectabilis (Fabaceae) extracts: Fast identification of new constituents and co-metabolites

Carregando...
Imagem de Miniatura

Data

2005-11-01

Autores

Pivatto, Marcos [UNESP]
Crotti, Antônio E. M.
Lopes, Norberto P.
Castro-Gamboa, Ian [UNESP]
De Rezende, Amanda [UNESP]
Viegas Jr., Cláudio [UNESP]
Young, Maria Claudia M.
Furlan, Maysa [UNESP]
Bolzani, Vanderlan da Silva [UNESP]

Título da Revista

ISSN da Revista

Título de Volume

Editor

Resumo

The fragmentation pattern of a homologous series of piperidine alkaloids isolated from S. spectabilis was investigated using electrospray ionization tandem mass spectrometry (ESI-MS/MS). The ESI-MS and ESI-MS/MS analyses of EtOH extracts and fractions from flowers and fruits of S. spectabilis allowed to elucidate the structures of four new compounds. The identification of these co-metabolites, based on the fragmentation patterns of previously isolated compounds, and further confirmed by accurate mass spectrometry defines this technique as a powerful tool to determine the metabolomic profile of species which has pharmacological importance. ©2005 Sociedade Brasileira de Química.

Descrição

Palavras-chave

Electrospray, Metabolomic profile, Piperidine alkaloids, Senna spectabilis, Tandem mass spectrometry

Como citar

Journal of the Brazilian Chemical Society, v. 16, n. 6 B, p. 1431-1438, 2005.