Detection of glucose and triglycerides using information visualization methods to process impedance spectroscopy data
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Data
2012-05-20
Autores
Moraes, Mark L.
Petri, Lais
Oliveira, Victor
Olivati, Clarissa A. [UNESP]
de Oliveira, Maria Cristina F.
Paulovich, Fernando V.
Oliveira, Osvaldo N.
Ferreira, Marystela
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Título de Volume
Editor
Elsevier B.V. Sa
Resumo
In this paper we discuss the detection of glucose and triglycerides using information visualization methods to process impedance spectroscopy data. The sensing units contained either lipase or glucose oxidase immobilized in layer-by-layer (LbL) films deposited onto interdigitated electrodes. The optimization consisted in identifying which part of the electrical response and combination of sensing units yielded the best distinguishing ability. It is shown that complete separation can be obtained for a range of concentrations of glucose and triglyceride when the interactive document map (IDMAP) technique is used to project the data into a two-dimensional plot. Most importantly, the optimization procedure can be extended to other types of biosensors, thus increasing the versatility of analysis provided by tailored molecular architectures exploited with various detection principles. (C) 2012 Elsevier B.V. All rights reserved.
Descrição
Palavras-chave
Nanostructured film, Biosensor, Information visualization, Multidimensional projection, Lipase, Glucose oxidase
Como citar
Sensors and Actuators B-chemical. Lausanne: Elsevier B.V. Sa, v. 166, p. 231-238, 2012.