Correlação entre a taxa de fertilização e o fuso meiótico em oócitos humanos: Uma meta-análise
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Data
2009-01-01
Autores
Petersen, Claudia Guilhermino
Oliveira, João Batista Alcantara [UNESP]
Mauri, Ana Lucia
Massaro, Fabiana C.
Baruffi, Ricardo
Pontes, Anaglória [UNESP]
Franco Junior, Jose Gonçalves [UNESP]
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Resumo
Objective: To investigate the relationship between the presence of meiotic spindle in human oocytes and fertilization rates in ICSI cycles. Methods: Search strategies included online surveys of databases from 1990 to 2008. Nine trials fulfilled the inclusion criteria Results: According to the meta-analysis, the results showed statistically significant higher fertilization rate (p<0.0001) when the meiotic spindle was viewed than when it was not. There was heterogeneity in this comparison. Conclusion: The presence of a birefringent meiotic spindle in human oocytes can predict a higher fertilization rate. This observation has clinical relevance mainly in countries where there is a legal limit on the number of oocytes to be fertilized. Copyright - SBRA - Sociedade Brasileira de Reprodução Assistida.
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Palavras-chave
Fertilization rate, Human oocyte, ICSI, Meiotic spindle, Meta-analysis, clinical trial, data analysis, data base, fertilization, human, information retrieval, intracytoplasmic sperm injection, meiosis, meiosis spindle, meta analysis, oocyte, oocyte maturation, systematic review
Como citar
Jornal Brasileiro de Reproducao Assistida, v. 13, n. 1, p. 25-28, 2009.