Repair of bone cavities in dog's mandible filled with inorganic bovine bone and bioactive glass associated with platelet rich plasma
Carregando...
Data
2011-05-13
Autores
Bassi, Ana Paula Farnezi [UNESP]
de Carvalho, Paulo Sérgio Perri [UNESP]
Título da Revista
ISSN da Revista
Título de Volume
Editor
Resumo
The aim of this study was to evaluate the effect of platelet rich plasma (PRP) associated to bovine inorganic bone (Bio-Oss®; Geistlich) or bioactive glass (Bio-Gran®; Orthovita, Implant Innovations) on bone healing. Bone cavities were prepared in both sides of the mandible of 4 adult male dogs. The cavities were divided into 4 groups according to the filling material as follows: control, PRP, PRP/Bio-Oss, PRP/Bio-Gran. The animals were sacrificed after 120 days and histological and histomorphometrical analysis was performed. The control group showed 80.6% of bone formation in the longitudinal sections at 6 mm depth and 83.7% at 13 mm depth. The transverse sections displayed 74.2% at both 6 and 13 mm depths. The PRP group showed 21.1% of bone formation in the longitudinal sections at 6 mm depth, and 23.1% at 13 mm depth. The transverse sections presented 28.98% of bone formation at 6 mm depth and 41.2% at 13 mm depth. The PRP/Bio-Gran group showed 25.1% of bone formation in the longitudinal sections at 6 mm depth and 30.4% at 13 mm depth. In the transverse sections, the bone formation was 43.0% at 6 mm depth and 39.7% at 13 mm depth. The PRP/Bio-Oss group showed 35.5% of bone formation in the longitudinal sections at 6 mm depth and 42% at 13 mm depth. In the transversal sections, the bone formation was 26.8% and 31.2% at the depths of 6 and 13 mm, respectively. PRP alone or associated with bovine inorganic bone or bioglass had no significant effect in bone healing.
Descrição
Palavras-chave
Bioactive glass, Inorganic bovine bone, Platelet rich plasma, Bio Oss, Bio-Oss, Biogran, biomaterial, glass, mineral, animal, bone prosthesis, bone regeneration, cattle, dog, drug effect, evaluation, male, mandible, thrombocyte rich plasma, Animals, Biocompatible Materials, Bone Regeneration, Bone Substitutes, Cattle, Dogs, Glass, Male, Mandible, Minerals, Platelet-Rich Plasma
Como citar
Brazilian Dental Journal, v. 22, n. 1, p. 14-20, 2011.