Gastrointestinal changes associated to heart failure
Carregando...
Data
2012-03-01
Autores
Romeiro, Fernando Gomes [UNESP]
Okoshi, Katashi [UNESP]
Zornoff, Leonardo Antonio Mamede [UNESP]
Okoshi, Marina Politi [UNESP]
Título da Revista
ISSN da Revista
Título de Volume
Editor
Resumo
Over the last decade, several studies were conducted on the gastrointestinal changes associated to chronic heart failure. This article presents a literature review on the physiopathology and clinical consequences of pathological digestive changes of heart failure patients. Structural and functional abnormalities of the gastrointestinal tract, such as edema of absorptive mucosa and intestinal bacterial overgrowth, have been leading to serious clinical consequences. Some of these consequences are cardiac cachexia, systemic inflammatory activation and anemia. These conditions, alone or in combination, may lead to worsening of the pre-existing ventricular dysfunction. Although currently there is no therapy specifically earmarked for gastrointestinal changes associated to heart failure, the understanding of digestive abnormalities is germane for the prevention and management of systemic consequences.
Descrição
Palavras-chave
Abnormalities of the digestive system, Anemia, Cachexia, Heart failure/complications, Intestinal absorption, acetylcysteine, bacterium lipopolysaccharide, diuretic agent, endotoxin, etanercept, immunoglobulin, infliximab, interleukin 1 receptor blocking agent, interleukin 10, iron, methotrexate, mitogen activated protein kinase p38 inhibitor, pentoxifylline, thalidomide, tumor necrosis factor alpha, tumor necrosis factor alpha converting enzyme inhibitor, anemia, bacterial overgrowth, cachexia, diet therapy, edema, exercise, gastrointestinal absorption, gastrointestinal change, gastrointestinal disease, heart failure, heart ventricle function, human, immunomodulation, inflammation, intestine flora, intestine mucosa permeability, iron deficiency, pathophysiology, review, stomach antrum vascular ectasia, stomach mucosa, telangiectasia, Gastrointestinal Diseases, Heart Failure, Humans, Inflammation, Intestinal Absorption, Intestines
Como citar
Arquivos Brasileiros de Cardiologia, v. 98, n. 3, p. 273-277, 2012.