Nanotechnology-based drug delivery systems for treatment of hyperproliferative skin diseases - a review
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Data
2013-04-12
Autores
dos Santos, Fernanda Kolenyak [UNESP]
Oyafuso, Marcia Helena [UNESP]
Kiill, Charlene Priscila [UNESP]
Daflon-Gremião, Maria Palmira [UNESP]
Chorilli, Marlus [UNESP]
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Resumo
The chronic hyperproliferative diseases (CHD) include cancer, precancerous lesions and diseases of unknown etiology such as psoriasis. Various drugs have been used in the treatment of CHD, such as antiproliferative and corticosteroids in general. However, some drugs have properties that limit their effectiveness, such as low solubility in water and low penetration of the skin. Thus, the control of drug release in the skin may improve efficacy and reduce side effects of many drugs used in hyperproliferative diseases. The purpose of this study was to make a systematic review of nanotechnology-based drug delivery systems used against hyperproliferative skin diseases. © 2013 Bentham Science Publishers.
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Palavras-chave
Chronic hyperoproliferative diseases, Drug delivery systems, Nanotechnology, Psoriasis, Skin cancer, Skin diseases, Skin treatment, Anti-proliferative, Drug delivery system, Drug release, Skin cancers, Skin disease, Solubility in waters, Systematic Review, Dermatology, Disease control, Drug delivery, Drug interactions, Drug products, Diseases, aminolevulinic acid, benzopsoralen 3 ethoxy carbonyl 2h benzofuro[3,2 e] 1 benzopiran 2 one, chitosan derivative, clobetasol propionate, corticosteroid, etretin, fluorouracil, glycerol behenate, ketoprofen, methotrexate, methoxsalen, n sulfonate n,o carboxymethylchitosan, nanocapsule, nanocoating, paclitaxel, phosphatidylcholine, podophyllotoxin, poloxamer, polymer, polymeric nanoparticle, polymethacrylic acid, psoralen derivative, retinoic acid, solid lipid nanoparticle, spantide, tacrolimus, temoporfin, triamcinolone acetonide, unclassified drug, biodegradability, burning sensation, cell differentiation, cell viability, chronic hyperproliferative disease, contact dermatitis, cream, dermatitis, drug absorption, drug cytotoxicity, drug delivery system, drug efficacy, drug penetration, drug release, drug retention, drug safety, drug solubility, encapsulation, erythema, human, injection site pruritus, iontophoresis, keratinocyte, liquid crystal, microemulsion, nanomedicine, nanotechnology, photochemotherapy, photodynamic therapy, photosensitivity, precancer, priority journal, psoriasis, PUVA, skin allergy, skin cancer, skin disease, skin infection, skin penetration, skin tumor, stratum corneum, systematic review, T lymphocyte, topical treatment, ultraviolet A radiation, ultraviolet B radiation
Como citar
Current Nanoscience, v. 9, n. 1, p. 159-167, 2013.