Intermediate reactive oxygen and nitrogen from macrophages induced by Brazilian lichens
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Data
2004-07-01
Autores
Santos, Lourdes Campaner dos [UNESP]
Honda, N. K.
Carlos, I. Z.
Vilegas, Wagner [UNESP]
Título da Revista
ISSN da Revista
Título de Volume
Editor
Elsevier B.V.
Resumo
The activity of ten compounds isolated from Brazilian lichen over the release of hydrogen peroxide and nitric oxide was evaluated in the culture of peritoneal macrophage cells from mice. Salazinic, secalonic A and fumarprotocetraric acids were the compounds that induced the greatest release of H2O2, whereas 12R-usnic and diffractaic acids induced the release of NO. These results indicate that lichen products have potential immunological modulating activities. (C) 2004 Elsevier B.V. All rights reserved.
Descrição
Palavras-chave
lichens, macrophages, peroxide hydrogen, nitric oxide
Como citar
Fitoterapia. Amsterdam: Elsevier B.V., v. 75, n. 5, p. 473-479, 2004.