Flavonoids and a naphthopyranone from Eriocaulon ligulatum and their mutagenic activity
Carregando...
Data
2007-11-01
Autores
da Silva, Marcelo Aparecido [UNESP]
Siqueira Oliveira, Ana Paula [UNESP]
Sannomiya, Miriam [UNESP]
Sano, Paulo Takeo
Varanda, Eliana Aparecida [UNESP]
Vilegas, Wagner [UNESP]
Santos, Lourdes Campaner dos [UNESP]
Título da Revista
ISSN da Revista
Título de Volume
Editor
Pharmaceutical Soc Japan
Resumo
A new acylated flavonoid, 6,4'-dimethoxyquereetin-3-O-beta-D-6 ''[3,4,5-trihydroxy (E)-cinnamoyl]glucopyranoside, and a naphthopyranone dimer, named eriocauline, together with 2 other known flavonoids, 6-methoxyapigenin-7-O-beta-D-glucopyranoside and 6-methoxyapigenin-7-O-beta-D-allopyranoside, have been isolated from the capitulae of Eriocaulon ligulatum. The compounds were identified using spectroscopic methods (HR-ESI-MS, and 1-D and 2-D NMR). The methanol extract exhibited mutagenic activity in the Salmonella/microsome assay, in strains TA100, TA97a and TA102 and for dichloromethane extract tested in strain TA98.
Descrição
Palavras-chave
Eriocaulon ligulatum, Eriocaulaceae, naphthopyranone, flavonoid, Ames test, high speed counter-current chromatography
Como citar
Chemical & Pharmaceutical Bulletin. Tokyo: Pharmaceutical Soc Japan, v. 55, n. 11, p. 1635-1639, 2007.