Validation of the brazilian version of the apathy inventory

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2013-09-01

Autores

Stella, Florindo [UNESP]
De Andrade, Larissa Pires [UNESP]
Garuffi, Marcelo [UNESP]
Vital, Thays Martins [UNESP]
Hernández, Salma Stephany Soleman [UNESP]
Ruocco, Marcela
Sé, Elisandra Villela Gasparetto
Klein, Margarete
Martins, Tânia
Robert, Philippe H.

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Background Apathy is a frequent neuropsychiatric condition in neurodegenerative disorders, depression, and often in mild cognitive impairment. The Apathy Inventory (AI) is a reliable instrument for improving the accuracy of the apathy diagnosis. The aim was to establish the validity of the Apathy Inventory for the Brazilian community. Methods We established the concurrent validity, internal consistency, inter-rater reliability, and the sensitivity and specificity of AI for the Brazilian community in a cohort of 175 individuals with Alzheimer's disease, Parkinson's disease, depression, mild cognitive impairment, and healthy controls. The three dimensions of the AI (emotional blunting, lack of initiative, and lack of interest) were compared with the Apathy domain of the Neuropsychiatric Inventory-Clinician rating scale (NPI-C) in an independent scheme. Results The analyses demonstrated high correlation coefficients in AI's individual dimensions and in AI-total score (F = 0.965). Concerning the NPI-C/Apathy domain, intra-class correlation coefficients were also high (F = 0.977). Concurrent validity was high according to both raters on AI dimensions × NPI-C/Apathy domain and regarding total score (rater 1: rho = 0.956 vs. rater 2: rho = 0.970). The internal consistency of the AI was also high concerning the AI's individual dimensions and total score (rater 1: 0.945 vs. rater 2: 0.958). Conclusion We observed high internal consistency, high concurrent validity, and inter-rater reliability of the Apathy Inventory. In addition, we found that its sensitivity and specificity were high. We suggest that the Brazilian version of the Apathy Inventory would be an appropriate instrument to identify the apathy syndrome in Brazilian patients. © 2012 John Wiley & Sons, Ltd.

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Alzheimer's disease, apathy, depression, mild cognitive impairment, Parkinson's disease, scales, adult, aged, Alzheimer disease, Apathy Inventory, cohort analysis, concurrent validity, controlled study, correlation coefficient, female, human, internal consistency, interrater reliability, major clinical study, male, named inventories, questionnaires and rating scales, neuropsychiatric inventory clinician rating scale, Parkinson disease, rating scale, sensitivity and specificity

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International Journal of Geriatric Psychiatry, v. 28, n. 9, p. 979-986, 2013.