Introducing polymer conductance in diagnostically relevant transduction

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dc.contributor.authorBaradoke, Ausra
dc.contributor.authorSantos, Adriano [UNESP]
dc.contributor.authorBueno, Paulo R. [UNESP]
dc.contributor.authorDavis, Jason J.
dc.contributor.institutionUniversity of Oxford
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2021-06-25T11:06:33Z
dc.date.available2021-06-25T11:06:33Z
dc.date.issued2021-01-15
dc.description.abstractIn this work we demonstrate that an impedance derived capacitance method is able to cleanly resolve the resonant conductance characteristics of an electrode-confined polymer film. In decorating the film with receptors, this conductance is thereafter modulated by the capturing of specific targets, demonstrated herein with C-reactive protein. This entirely reagentless and single step marker quantification is relevant to the drive of moving assays to a scaleable format requiring minimal user intervention.en
dc.description.affiliationDepartment of Chemistry University of Oxford, South Parks Road, Oxford OX1 3QZ
dc.description.affiliationInstitute of Chemistry São Paulo State University (UNESP), São Paulo
dc.description.affiliationUnespInstitute of Chemistry São Paulo State University (UNESP), São Paulo
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipInnovate UK
dc.identifierhttp://dx.doi.org/10.1016/j.bios.2020.112705
dc.identifier.citationBiosensors and Bioelectronics, v. 172.
dc.identifier.doi10.1016/j.bios.2020.112705
dc.identifier.issn1873-4235
dc.identifier.issn0956-5663
dc.identifier.scopus2-s2.0-85095432701
dc.identifier.urihttp://hdl.handle.net/11449/208114
dc.language.isoeng
dc.relation.ispartofBiosensors and Bioelectronics
dc.sourceScopus
dc.subjectBiosensors
dc.subjectC-reactive protein
dc.subjectMolecular scale conductance
dc.subjectPoint-of-care
dc.subjectReagentless
dc.titleIntroducing polymer conductance in diagnostically relevant transductionen
dc.typeArtigo

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