Comparison of morphometry and ventricular function of healthy and smoking young people

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dc.contributor.authorRibeiro Batista, Ana Natalia [UNESP]
dc.contributor.authorGarcia, Thais [UNESP]
dc.contributor.authorThome Franco, Estefania Aparecida [UNESP]
dc.contributor.authorAzevedo, Paula Schmidt [UNESP]
dc.contributor.authorBarbosa, Mauricio Fregonesi [UNESP]
dc.contributor.authorMamede Zornoff, Leonardo Antonio [UNESP]
dc.contributor.authorMinicucci, Marcos Ferreira [UNESP]
dc.contributor.authorRupp de Paiva, Sergio Alberto [UNESP]
dc.contributor.authorZucchi, Jose William [UNESP]
dc.contributor.authorGodoy, Irma de [UNESP]
dc.contributor.authorTanni, Suzana Erico [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2020-12-10T19:49:04Z
dc.date.available2020-12-10T19:49:04Z
dc.date.issued2020-02-06
dc.description.abstractBackground Tobacco smoke is one of the most significant risk factors for cardiovascular diseases and damages in the myocardial tissue directly. Cardiac magnetic resonance (CMR) has been used and is a promising tool to evaluate morphometry and cardiac function in humans. The objective of this study was to evaluate associations of smoking with morphometry and cardiac function by CMR technique in young adult smokers. Methods Altogether, 49 volunteers (22 smokers and 27 non-smokers) were included in the study. The comparisons between groups were performed by multiple linear regression adjusting for body mass index and gender. Results In the morphometric and functional evaluation of the left ventricle, we observed statistical significant lower values of end-diastolic volume (EDV) (p = 0.02), ejection volume (EV) (p = 0.001) and indexed ejection volume (IEV) (p = 0.007) in smokers when compared to no-smoker group. Right ventricle showed statistical significant lower values of EDV (p = < 0.001), end-systolic volume (p = 0.01), EV (p = < 0.001), IEV (p = 0.001), indexed end-diastolic volume (p = 0.001) and major axis (p = 0.01) in smokers when compared to non-smokers group. Conclusions There is a strongly association of smoking in young adult and cardiac function decline, even adjusted by cofounders, which compromises the proper functioning of the heart. Evidence confirms that smoking can directly influence the cardiac function, even without atherosclerosis or other chronic comorbidities, associated with increased risk of cardiovascular diseases.en
dc.description.affiliationUniv Estadual Paulista, UNESP, Univ Estadual Paulista, Botucatu Sch Med,Dept Clin Med, Botucatu, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, UNESP, Univ Estadual Paulista, Botucatu Sch Med,Dept Clin Med, Botucatu, SP, Brazil
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipIdFAPESP: 2015/06772-0
dc.format.extent7
dc.identifierhttp://dx.doi.org/10.1186/s12872-020-01372-w
dc.identifier.citationBmc Cardiovascular Disorders. London: Bmc, v. 20, n. 1, 7 p., 2020.
dc.identifier.doi10.1186/s12872-020-01372-w
dc.identifier.issn1471-2261
dc.identifier.urihttp://hdl.handle.net/11449/196568
dc.identifier.wosWOS:000512696300003
dc.language.isoeng
dc.publisherBmc
dc.relation.ispartofBmc Cardiovascular Disorders
dc.sourceWeb of Science
dc.subjectCardiovascular magnetic resonance
dc.subjectSmoking
dc.subjectHeart
dc.subjectVentricular function
dc.titleComparison of morphometry and ventricular function of healthy and smoking young peopleen
dc.typeArtigo
dcterms.rightsHolderBmc
unesp.author.orcid0000-0002-6557-2275[5]

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